The Anzhen Risk Scoring System for Acute Type A Aortic Dissection: A Prospective Observational Study Protocol
Introduction: Acute type A aortic dissection (ATAAD) is a catastrophic disease with fatal outcomes. Malperfusion syndrome (MPS) is a serious complication of ATAAD, with an incidence of 20–40%. Many studies have shown that MPS is the main risk factor for poor ATAAD prognosis. However, a risk scoring...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Compuscript Ltd
2023-01-01
|
| Series: | Cardiovascular Innovations and Applications |
| Online Access: | https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0002 |
| _version_ | 1797454465957101568 |
|---|---|
| author | Bo Jia Cheng Luo Chengnan Li Yipeng Ge Yongliang Zhong Zhiyu Qiao Haiou Hu Suwei Chen Junming Zhu |
| author_facet | Bo Jia Cheng Luo Chengnan Li Yipeng Ge Yongliang Zhong Zhiyu Qiao Haiou Hu Suwei Chen Junming Zhu |
| author_sort | Bo Jia |
| collection | DOAJ |
| description | Introduction: Acute type A aortic dissection (ATAAD) is a catastrophic disease with fatal outcomes. Malperfusion syndrome (MPS) is a serious complication of ATAAD, with an incidence of 20–40%. Many studies have shown that MPS is the main risk factor for poor ATAAD prognosis. However, a risk scoring system for ATAAD based on MPS is lacking. Here, we designed a risk scoring system for ATAAD to assess mortality through quantitative assessment of relevant organ malperfusion and subsequently develop rational treatment strategies. Methods and analysis: This was a prospective observational study. Patients’ perioperative clinical data were collected to establish a database of ATAAD (N≥3000) and determine whether these patients had malperfusion complications. The Anzhen risk scoring system was established on the basis of organ malperfusion by using a random forest survival model and a logistics model. The better method was then chosen to establish a revised risk scoring system. Ethics and dissemination: This study received ethical approval from the Ethics Committees of Beijing Anzhen Hospital, Capital Medical University (KS2019034-1). Patient consent was waived because biological samples were not collected, and no patient rights were violated. Findings will be disseminated at scientific conferences and in peer-reviewed publications. |
| first_indexed | 2024-03-09T15:37:38Z |
| format | Article |
| id | doaj.art-0e0d0e89e6164d138a15168a0ebf2bb5 |
| institution | Directory Open Access Journal |
| issn | 2009-8618 2009-8782 |
| language | English |
| last_indexed | 2024-03-09T15:37:38Z |
| publishDate | 2023-01-01 |
| publisher | Compuscript Ltd |
| record_format | Article |
| series | Cardiovascular Innovations and Applications |
| spelling | doaj.art-0e0d0e89e6164d138a15168a0ebf2bb52023-11-25T17:00:43ZengCompuscript LtdCardiovascular Innovations and Applications2009-86182009-87822023-01-017198210.15212/CVIA.2023.0002The Anzhen Risk Scoring System for Acute Type A Aortic Dissection: A Prospective Observational Study ProtocolBo JiaCheng LuoChengnan LiYipeng GeYongliang ZhongZhiyu QiaoHaiou HuSuwei ChenJunming ZhuIntroduction: Acute type A aortic dissection (ATAAD) is a catastrophic disease with fatal outcomes. Malperfusion syndrome (MPS) is a serious complication of ATAAD, with an incidence of 20–40%. Many studies have shown that MPS is the main risk factor for poor ATAAD prognosis. However, a risk scoring system for ATAAD based on MPS is lacking. Here, we designed a risk scoring system for ATAAD to assess mortality through quantitative assessment of relevant organ malperfusion and subsequently develop rational treatment strategies. Methods and analysis: This was a prospective observational study. Patients’ perioperative clinical data were collected to establish a database of ATAAD (N≥3000) and determine whether these patients had malperfusion complications. The Anzhen risk scoring system was established on the basis of organ malperfusion by using a random forest survival model and a logistics model. The better method was then chosen to establish a revised risk scoring system. Ethics and dissemination: This study received ethical approval from the Ethics Committees of Beijing Anzhen Hospital, Capital Medical University (KS2019034-1). Patient consent was waived because biological samples were not collected, and no patient rights were violated. Findings will be disseminated at scientific conferences and in peer-reviewed publications.https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0002 |
| spellingShingle | Bo Jia Cheng Luo Chengnan Li Yipeng Ge Yongliang Zhong Zhiyu Qiao Haiou Hu Suwei Chen Junming Zhu The Anzhen Risk Scoring System for Acute Type A Aortic Dissection: A Prospective Observational Study Protocol Cardiovascular Innovations and Applications |
| title | The Anzhen Risk Scoring System for Acute Type A Aortic Dissection: A Prospective Observational Study Protocol |
| title_full | The Anzhen Risk Scoring System for Acute Type A Aortic Dissection: A Prospective Observational Study Protocol |
| title_fullStr | The Anzhen Risk Scoring System for Acute Type A Aortic Dissection: A Prospective Observational Study Protocol |
| title_full_unstemmed | The Anzhen Risk Scoring System for Acute Type A Aortic Dissection: A Prospective Observational Study Protocol |
| title_short | The Anzhen Risk Scoring System for Acute Type A Aortic Dissection: A Prospective Observational Study Protocol |
| title_sort | anzhen risk scoring system for acute type a aortic dissection a prospective observational study protocol |
| url | https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0002 |
| work_keys_str_mv | AT bojia theanzhenriskscoringsystemforacutetypeaaorticdissectionaprospectiveobservationalstudyprotocol AT chengluo theanzhenriskscoringsystemforacutetypeaaorticdissectionaprospectiveobservationalstudyprotocol AT chengnanli theanzhenriskscoringsystemforacutetypeaaorticdissectionaprospectiveobservationalstudyprotocol AT yipengge theanzhenriskscoringsystemforacutetypeaaorticdissectionaprospectiveobservationalstudyprotocol AT yongliangzhong theanzhenriskscoringsystemforacutetypeaaorticdissectionaprospectiveobservationalstudyprotocol AT zhiyuqiao theanzhenriskscoringsystemforacutetypeaaorticdissectionaprospectiveobservationalstudyprotocol AT haiouhu theanzhenriskscoringsystemforacutetypeaaorticdissectionaprospectiveobservationalstudyprotocol AT suweichen theanzhenriskscoringsystemforacutetypeaaorticdissectionaprospectiveobservationalstudyprotocol AT junmingzhu theanzhenriskscoringsystemforacutetypeaaorticdissectionaprospectiveobservationalstudyprotocol AT bojia anzhenriskscoringsystemforacutetypeaaorticdissectionaprospectiveobservationalstudyprotocol AT chengluo anzhenriskscoringsystemforacutetypeaaorticdissectionaprospectiveobservationalstudyprotocol AT chengnanli anzhenriskscoringsystemforacutetypeaaorticdissectionaprospectiveobservationalstudyprotocol AT yipengge anzhenriskscoringsystemforacutetypeaaorticdissectionaprospectiveobservationalstudyprotocol AT yongliangzhong anzhenriskscoringsystemforacutetypeaaorticdissectionaprospectiveobservationalstudyprotocol AT zhiyuqiao anzhenriskscoringsystemforacutetypeaaorticdissectionaprospectiveobservationalstudyprotocol AT haiouhu anzhenriskscoringsystemforacutetypeaaorticdissectionaprospectiveobservationalstudyprotocol AT suweichen anzhenriskscoringsystemforacutetypeaaorticdissectionaprospectiveobservationalstudyprotocol AT junmingzhu anzhenriskscoringsystemforacutetypeaaorticdissectionaprospectiveobservationalstudyprotocol |