Asymptomatic Bacteriuria in Patients with Diabetes Mellitus
Background: Asymptomatic bacteriuria is a common problem in diabetic patients and is associated with risk of septicemia and pyelonephritis if untreated. The diagnosis is based on urine culture. The incidence of antibiotic resistance has been steadily increasing over the past few years resulting...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Pvt. Ltd.
2013-04-01
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| Series: | National Journal of Laboratory Medicine |
| Subjects: | |
| Online Access: | http://www.njlm.net/articles/PDF/1983/3%20-%205761_E(_)_F(H)_PF1(HPrashobh)_PFA(H)_OLF.pdf |
| Summary: | Background: Asymptomatic bacteriuria is a common
problem in diabetic patients and is associated with risk of
septicemia and pyelonephritis if untreated. The diagnosis
is based on urine culture. The incidence of antibiotic
resistance has been steadily increasing over the past few
years resulting in limitation of therapeutic options.
Aims & Objectives: This study was carried out to determine
the prevalence of asymptomatic bacteriuria in diabetic
patients and also to isolate, identify and establish the
antimicrobial susceptibility pattern of the pathogens.
Materials & Methods: This prospective study includes 1000
diabetic patients. Isolates were identified by conventional methods
and their antibiotic susceptibility pattern was established.
Statistical Analysis: The results were analyzed using
mean, median and Chi-square (χ2) test.
Results: A total of 120 (12%) were positive for significant
bacteriuria. Escherichia coli was the most predominant
organism followed by Klebsiella pneumoniae. Imipenem,
pipercillin-tazobactum, nitrofurantoin and amikacin were
found to be the most effective antibiotics against the urinary
isolates.
Conclusion: The prevalence of asymptomatic bacteriuria is
high in diabetic patients and poor glucose control can be
considered as a predisposing factor. Routine urine culture is
recommended, especially for the detection of asymptomatic
bacteriuria cases in diabetic patients. |
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| ISSN: | 2277-8551 2455-6882 |