Immunoglobulin G4-Related Myocarditis with Eosinophilic Infiltration: A Case Report

Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) is a fibroinflammatory disorder that can involve any organ system; however, myocarditis is extremely rare. A 52-year-old male with dyspnea and chest discomfort underwent cardiac MRI that revealed edema and nodular, patchy, mesocardial and subendoa...

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Bibliographic Details
Main Authors: Hyun Woo, Song Soo Kim, Kye Taek Ahn, Seon Ah Jin, Hyeyoung Kwon
Format: Article
Language:English
Published: The Korean Society of Radiology 2023-05-01
Series:Journal of the Korean Society of Radiology
Subjects:
Online Access:https://doi.org/10.3348/jksr.2022.0058
Description
Summary:Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) is a fibroinflammatory disorder that can involve any organ system; however, myocarditis is extremely rare. A 52-year-old male with dyspnea and chest discomfort underwent cardiac MRI that revealed edema and nodular, patchy, mesocardial and subendoardial delayed enhancement of left ventricle, suggesting myocarditis. Laboratory findings revealed elevated serum IgG4 and eosinophilia. Cardiac biopsy confirmed eosinophilic myocarditis with IgG4-positive cells. Here, we present an unusual case of IgG4-RD manifesting as eosinophilic myocarditis.
ISSN:2951-0805