Pattern of postchemotherapy-associated complicatioins in a paediatric oncology service in Lagos: An observational study
Background: Globally, there is an increase in the number of pediatric oncology cases with significant morbidity and mortality in the low to middle income countries (LMIC) despite improved survival in the resource endowed nations. The increase in survival is largely due to the revolutionary use of mu...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2021-01-01
|
| Series: | Journal of Clinical Sciences |
| Subjects: | |
| Online Access: | http://www.jcsjournal.org/article.asp?issn=2468-6859;year=2021;volume=18;issue=2;spage=103;epage=108;aulast=Akinsete |
| _version_ | 1818715273398583296 |
|---|---|
| author | Adeseye Michael Akinsete Ugonna Olaraiche Fakile Emmanuella Ijeoma Nwobi Opeyemi Mercy Awofeso |
| author_facet | Adeseye Michael Akinsete Ugonna Olaraiche Fakile Emmanuella Ijeoma Nwobi Opeyemi Mercy Awofeso |
| author_sort | Adeseye Michael Akinsete |
| collection | DOAJ |
| description | Background: Globally, there is an increase in the number of pediatric oncology cases with significant morbidity and mortality in the low to middle income countries (LMIC) despite improved survival in the resource endowed nations. The increase in survival is largely due to the revolutionary use of multi strategy therapeutic interventions like chemotherapy, immunotherapy, surgery and radiotherapy. These modalities are however fraught with several complications. AIM The aim of this study was to prospectively observe and document the common complications following treatment of childhood cancers in a tertiary pediatric oncology unit in a resource constrained setting. Methods: This was a longitudinal observational study over a three-year period involving children with various cancers. Ethical approval was obtained from the hospital's human, research and ethics committee. A questionnaire was used to obtain socio-demographic data as well as details of adverse events encountered. Results: A total of 100 children enrolled in the study with acute lymphoblastic leukaemia been the commonest cancer. Gastrointestinal adverse events were the most common in the study cohort with alopecia rarely reported. Conclusion: Increased awareness of the common complications in this environment and prophylactic medications may improve the care of children post chemotherapy thereby reducing overall morbidity and cost of care. |
| first_indexed | 2024-12-17T19:00:45Z |
| format | Article |
| id | doaj.art-0e110605edc845faa3785116f22e0316 |
| institution | Directory Open Access Journal |
| issn | 2468-6859 2408-7408 |
| language | English |
| last_indexed | 2024-12-17T19:00:45Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Clinical Sciences |
| spelling | doaj.art-0e110605edc845faa3785116f22e03162022-12-21T21:36:07ZengWolters Kluwer Medknow PublicationsJournal of Clinical Sciences2468-68592408-74082021-01-0118210310810.4103/jcls.jcls_54_20Pattern of postchemotherapy-associated complicatioins in a paediatric oncology service in Lagos: An observational studyAdeseye Michael AkinseteUgonna Olaraiche FakileEmmanuella Ijeoma NwobiOpeyemi Mercy AwofesoBackground: Globally, there is an increase in the number of pediatric oncology cases with significant morbidity and mortality in the low to middle income countries (LMIC) despite improved survival in the resource endowed nations. The increase in survival is largely due to the revolutionary use of multi strategy therapeutic interventions like chemotherapy, immunotherapy, surgery and radiotherapy. These modalities are however fraught with several complications. AIM The aim of this study was to prospectively observe and document the common complications following treatment of childhood cancers in a tertiary pediatric oncology unit in a resource constrained setting. Methods: This was a longitudinal observational study over a three-year period involving children with various cancers. Ethical approval was obtained from the hospital's human, research and ethics committee. A questionnaire was used to obtain socio-demographic data as well as details of adverse events encountered. Results: A total of 100 children enrolled in the study with acute lymphoblastic leukaemia been the commonest cancer. Gastrointestinal adverse events were the most common in the study cohort with alopecia rarely reported. Conclusion: Increased awareness of the common complications in this environment and prophylactic medications may improve the care of children post chemotherapy thereby reducing overall morbidity and cost of care.http://www.jcsjournal.org/article.asp?issn=2468-6859;year=2021;volume=18;issue=2;spage=103;epage=108;aulast=Akinsetechemotherapycomplicationspediatric oncology |
| spellingShingle | Adeseye Michael Akinsete Ugonna Olaraiche Fakile Emmanuella Ijeoma Nwobi Opeyemi Mercy Awofeso Pattern of postchemotherapy-associated complicatioins in a paediatric oncology service in Lagos: An observational study Journal of Clinical Sciences chemotherapy complications pediatric oncology |
| title | Pattern of postchemotherapy-associated complicatioins in a paediatric oncology service in Lagos: An observational study |
| title_full | Pattern of postchemotherapy-associated complicatioins in a paediatric oncology service in Lagos: An observational study |
| title_fullStr | Pattern of postchemotherapy-associated complicatioins in a paediatric oncology service in Lagos: An observational study |
| title_full_unstemmed | Pattern of postchemotherapy-associated complicatioins in a paediatric oncology service in Lagos: An observational study |
| title_short | Pattern of postchemotherapy-associated complicatioins in a paediatric oncology service in Lagos: An observational study |
| title_sort | pattern of postchemotherapy associated complicatioins in a paediatric oncology service in lagos an observational study |
| topic | chemotherapy complications pediatric oncology |
| url | http://www.jcsjournal.org/article.asp?issn=2468-6859;year=2021;volume=18;issue=2;spage=103;epage=108;aulast=Akinsete |
| work_keys_str_mv | AT adeseyemichaelakinsete patternofpostchemotherapyassociatedcomplicatioinsinapaediatriconcologyserviceinlagosanobservationalstudy AT ugonnaolaraichefakile patternofpostchemotherapyassociatedcomplicatioinsinapaediatriconcologyserviceinlagosanobservationalstudy AT emmanuellaijeomanwobi patternofpostchemotherapyassociatedcomplicatioinsinapaediatriconcologyserviceinlagosanobservationalstudy AT opeyemimercyawofeso patternofpostchemotherapyassociatedcomplicatioinsinapaediatriconcologyserviceinlagosanobservationalstudy |