Insights into the Structural Conformations of the Tau Protein in Different Aggregation Status

Insights into the Structural Conformations of the Tau Protein in Different Aggregation Status

Tau is a protein characterized by large structural portions displaying extended conformational changes. Unfortunately, the accumulation of this protein into toxic aggregates in neuronal cells leads to a number of severe pathologies, collectively named tauopathies. In the last decade, significant res...

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Bibliographic Details
Main Authors: Luca Pinzi, Nicolò Bisi, Claudia Sorbi, Silvia Franchini, Nicolò Tonali, Giulio Rastelli
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Molecules
Subjects:
tau
protein conformations
tauopathies
Alzheimer’s disease
Online Access:https://www.mdpi.com/1420-3049/28/11/4544

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