Burkholderia pseudomallei BicA protein promotes pathogenicity in macrophages by regulating invasion, intracellular survival, and virulence

ABSTRACT Burkholderia pseudomallei (Bpm) is the causative agent of melioidosis disease. Bpm is a facultative intracellular pathogen with a complex life cycle inside host cells. Pathogenic success depends on a variety of virulence factors with one of the most critical being the type 6 secretion syste...

Full description

Bibliographic Details
Main Authors: Jacob L. Stockton, Nittaya Khakhum, Heather L. Stevenson, Alfredo G. Torres
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/msphere.00378-23