Hypertension in Prenatally Undernourished Young-Adult Rats Is Maintained by Tonic Reciprocal Paraventricular–Coerulear Excitatory Interactions

Hypertension in Prenatally Undernourished Young-Adult Rats Is Maintained by Tonic Reciprocal Paraventricular–Coerulear Excitatory Interactions

Prenatally malnourished rats develop hypertension in adulthood, in part through increased α<sub>1</sub>-adrenoceptor-mediated outflow from the paraventricular nucleus (PVN) to the sympathetic system. We studied whether both α<sub>1</sub>-adrenoceptor-mediated noradrenergic ex...

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Bibliographic Details
Main Authors: Bernardita Cayupe, Carlos Morgan, Gustavo Puentes, Luis Valladares, Héctor Burgos, Amparo Castillo, Alejandro Hernández, Luis Constandil, Miguel Ríos, Patricio Sáez-Briones, Rafael Barra
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
hypertension
prenatal undernutrition
paraventricular nucleus
locus coeruleus
noradrenaline
corticotropin-releasing factor
Online Access:https://www.mdpi.com/1420-3049/26/12/3568

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