Cytotoxic Activities, SAR and Anti-Invasion Effects of Butylphthalide Derivatives on Human Hepatocellular Carcinoma SMMC7721 Cells

Cytotoxic Activities, SAR and Anti-Invasion Effects of Butylphthalide Derivatives on Human Hepatocellular Carcinoma SMMC7721 Cells

A series of butylphthalide derivatives (BPDs) 1–8 were isolated from the extract of the dried rhizome of Ligusticum chuanxiong Hort. (Umbelliferae). The cytotoxic activities of BPDs 1–8 were evaluated using a panel of human cancer cell lines. In addition, the SAR analysis and potential anti-invasio...

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Bibliographic Details
Main Authors: Yihan Hu, Xiaoxu Bi, Pu Zhao, Huachuan Zheng, Xueshi Huang
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:Molecules
Subjects:
Ligusticum chuanxiong
butylphthalides
cytotoxic activity
SAR
anti-invasion
Online Access:http://www.mdpi.com/1420-3049/20/11/19699

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