Knockdown of protein interacting with C α kinase 1 aggravates sepsis-induced acute liver injury by regulating the TLR4/NF-κB pathway

Knockdown of protein interacting with C α kinase 1 aggravates sepsis-induced acute liver injury by regulating the TLR4/NF-κB pathway

Abstract Acute liver injury (ALI) may manifest at any phase of sepsis, yet an explicit therapeutic approach remains elusive. In this study, LPS and cecum ligation and puncture (CLP) were utilized to establish an inflammatory cell model and a murine model of sepsis-induced liver injury, respectively,...

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Bibliographic Details
Main Authors:	Huijun Wang, Ting Ma, Qianqian Bao, Lijun Zhu, Tingting Ying, Yulong Yu
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-07-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-023-38852-w

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