RADIONUCLIDE INDICATION OF SENTINEL LYMPH NODES IN LARYNX AND LARYNGOPHARYNX CANCER
Aim: to determine the possibility of radionuclide methods in the identification of "sentinel" lymph node (SLN) in larynx and laryngopharynx cancer patients.Material and methods: 17 patients with larynx and laryngopharynx cancer were included in research. In all patients for SLN visualizati...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2014-02-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/88 |
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| author | I. G. Sinilkin V. I. Chernov Ye. L. Choinzonov S. Yu. Chizhevskaya A. A. Titskaya R. V. Zelchan |
| author_facet | I. G. Sinilkin V. I. Chernov Ye. L. Choinzonov S. Yu. Chizhevskaya A. A. Titskaya R. V. Zelchan |
| author_sort | I. G. Sinilkin |
| collection | DOAJ |
| description | Aim: to determine the possibility of radionuclide methods in the identification of "sentinel" lymph node (SLN) in larynx and laryngopharynx cancer patients.Material and methods: 17 patients with larynx and laryngopharynx cancer were included in research. In all patients for SLN visualization nanocolloid radiopharmaceutical was injection around tumor into mucous coat with the subsequent SPECT and radioguided study.Results: Sensitivity and specificity of SPECT and radioguided study for SLN identification were 100%. We found 22 SLN in 17 patients (from 1 to 2 per patient, on average 1.3). Most often SLN were located in the III level of a neck (lymph nodes around of carotid arteries) – 12 SLN (54.5%) and IIA level (under lower jaw lymph nodes) – 6 (27.2%). One SLN (4.5%) was localized in IV level and 3 nodes (13.6%) in VI level. In 2 patients (11.8%) metastasis in SLN were found. In these patients within 2 years cancer progressing was revealed. Fifteen patients (88.2%) had no metastatic in SLN and had no progressing of a cancer.Conclusions: Sensitivity and specificity of SPECT and radioguided study for SLN identification are 100%. In patients with metastatic SLN radical surgery with lymph node dissection is helpful. |
| first_indexed | 2024-04-10T01:08:18Z |
| format | Article |
| id | doaj.art-0e1cc476e73e4f8ca63d66980a629ad6 |
| institution | Directory Open Access Journal |
| issn | 1682-0363 1819-3684 |
| language | English |
| last_indexed | 2024-04-10T01:08:18Z |
| publishDate | 2014-02-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj.art-0e1cc476e73e4f8ca63d66980a629ad62023-03-13T09:58:19ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842014-02-0113111612110.20538/1682-0363-2014-1-116-12186RADIONUCLIDE INDICATION OF SENTINEL LYMPH NODES IN LARYNX AND LARYNGOPHARYNX CANCERI. G. Sinilkin0V. I. Chernov1Ye. L. Choinzonov2S. Yu. Chizhevskaya3A. A. Titskaya4R. V. Zelchan5Научно-исследовательский институт онкологии Сибирского отделения РАМН, ТомскНаучно-исследовательский институт онкологии Сибирского отделения РАМН, ТомскНаучно-исследовательский институт онкологии Сибирского отделения РАМН, Томск, Сибирский государственный медицинский университет, ТомскНаучно-исследовательский институт онкологии Сибирского отделения РАМН, ТомскНаучно-исследовательский институт онкологии Сибирского отделения РАМН, ТомскНаучно-исследовательский институт онкологии Сибирского отделения РАМН, ТомскAim: to determine the possibility of radionuclide methods in the identification of "sentinel" lymph node (SLN) in larynx and laryngopharynx cancer patients.Material and methods: 17 patients with larynx and laryngopharynx cancer were included in research. In all patients for SLN visualization nanocolloid radiopharmaceutical was injection around tumor into mucous coat with the subsequent SPECT and radioguided study.Results: Sensitivity and specificity of SPECT and radioguided study for SLN identification were 100%. We found 22 SLN in 17 patients (from 1 to 2 per patient, on average 1.3). Most often SLN were located in the III level of a neck (lymph nodes around of carotid arteries) – 12 SLN (54.5%) and IIA level (under lower jaw lymph nodes) – 6 (27.2%). One SLN (4.5%) was localized in IV level and 3 nodes (13.6%) in VI level. In 2 patients (11.8%) metastasis in SLN were found. In these patients within 2 years cancer progressing was revealed. Fifteen patients (88.2%) had no metastatic in SLN and had no progressing of a cancer.Conclusions: Sensitivity and specificity of SPECT and radioguided study for SLN identification are 100%. In patients with metastatic SLN radical surgery with lymph node dissection is helpful.https://bulletin.ssmu.ru/jour/article/view/88рак гортанирак гортаноглоткисторожевые лимфатические узлы |
| spellingShingle | I. G. Sinilkin V. I. Chernov Ye. L. Choinzonov S. Yu. Chizhevskaya A. A. Titskaya R. V. Zelchan RADIONUCLIDE INDICATION OF SENTINEL LYMPH NODES IN LARYNX AND LARYNGOPHARYNX CANCER Бюллетень сибирской медицины рак гортани рак гортаноглотки сторожевые лимфатические узлы |
| title | RADIONUCLIDE INDICATION OF SENTINEL LYMPH NODES IN LARYNX AND LARYNGOPHARYNX CANCER |
| title_full | RADIONUCLIDE INDICATION OF SENTINEL LYMPH NODES IN LARYNX AND LARYNGOPHARYNX CANCER |
| title_fullStr | RADIONUCLIDE INDICATION OF SENTINEL LYMPH NODES IN LARYNX AND LARYNGOPHARYNX CANCER |
| title_full_unstemmed | RADIONUCLIDE INDICATION OF SENTINEL LYMPH NODES IN LARYNX AND LARYNGOPHARYNX CANCER |
| title_short | RADIONUCLIDE INDICATION OF SENTINEL LYMPH NODES IN LARYNX AND LARYNGOPHARYNX CANCER |
| title_sort | radionuclide indication of sentinel lymph nodes in larynx and laryngopharynx cancer |
| topic | рак гортани рак гортаноглотки сторожевые лимфатические узлы |
| url | https://bulletin.ssmu.ru/jour/article/view/88 |
| work_keys_str_mv | AT igsinilkin radionuclideindicationofsentinellymphnodesinlarynxandlaryngopharynxcancer AT vichernov radionuclideindicationofsentinellymphnodesinlarynxandlaryngopharynxcancer AT yelchoinzonov radionuclideindicationofsentinellymphnodesinlarynxandlaryngopharynxcancer AT syuchizhevskaya radionuclideindicationofsentinellymphnodesinlarynxandlaryngopharynxcancer AT aatitskaya radionuclideindicationofsentinellymphnodesinlarynxandlaryngopharynxcancer AT rvzelchan radionuclideindicationofsentinellymphnodesinlarynxandlaryngopharynxcancer |