Personal and Social Resources Are Linked to Cognition and Health-Related Quality of Life in Childhood Cancer Survivors
Personal and social resources may buffer the adverse effects of childhood cancer and its impact on cognition and quality of life. While childhood cancer survivors show domain-specific cognitive difficulties, little is known about their personal and social resources. We therefore investigated persona...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/9/7/936 |
| _version_ | 1797433712726507520 |
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| author | Valerie Siegwart Kirstin Schürch Valentin Benzing Jochen Roessler Regula Everts |
| author_facet | Valerie Siegwart Kirstin Schürch Valentin Benzing Jochen Roessler Regula Everts |
| author_sort | Valerie Siegwart |
| collection | DOAJ |
| description | Personal and social resources may buffer the adverse effects of childhood cancer and its impact on cognition and quality of life. While childhood cancer survivors show domain-specific cognitive difficulties, little is known about their personal and social resources. We therefore investigated personal and social resources and their association with cognitive and quality-of-life outcomes in childhood cancer survivors. Seventy-eight survivors of childhood cancer of different etiologies (aged 7–16 years; ≥one year since treatment) and fifty-six healthy controls were included. Cognitive outcome was assessed by neuropsychological tests; personal and social resources, as well as health-related quality of life, were assessed by standardized questionnaires. In the social resource domain, peer integration was worse in survivors than in controls (<i>p</i><sub>uncorr</sub> < 0.04, <i>d</i> = 0.33). Personal resources and all other subscales of social resources did not significantly differ between survivors and controls. In survivors, the global resource score was significantly correlated with processing speed (<i>r</i> = 0.39, <i>p</i><sub>corr</sub> < 0.001) and quality of life (parent: <i>r</i> = 0.44; self-report: <i>r</i> = 0.46; <i>p</i><sub>scorr</sub> < 0.001). In controls, no association occurred between resources and cognitive outcome, and the correlation between the global resource score and quality of life did not withstand correction for multiple comparison (parent: <i>r</i> = 0.28; self-report: <i>r</i> = 0.40, <i>p</i><sub>suncorr</sub> < 0.001). After an adverse event such as childhood cancer, resources might play a particularly buffering role on cognitive performance and quality of life (when compared to the everyday life of healthy controls). This highlights the importance of interventions that strengthen the resources of children and their families, even years after cancer. Such resource-focused intervention could help to counteract long-term sequelae in cognitive outcomes and health-related quality of life. |
| first_indexed | 2024-03-09T10:20:55Z |
| format | Article |
| id | doaj.art-0e1d91a934494338b44aa078c5a1f7e1 |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-09T10:20:55Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-0e1d91a934494338b44aa078c5a1f7e12023-12-01T22:01:17ZengMDPI AGChildren2227-90672022-06-019793610.3390/children9070936Personal and Social Resources Are Linked to Cognition and Health-Related Quality of Life in Childhood Cancer SurvivorsValerie Siegwart0Kirstin Schürch1Valentin Benzing2Jochen Roessler3Regula Everts4Division of Pediatric Hematology and Oncology, Department of Pediatrics, Inselspital Bern University Hospital, University of Bern, 3010 Bern, SwitzerlandDivision of Pediatric Hematology and Oncology, Department of Pediatrics, Inselspital Bern University Hospital, University of Bern, 3010 Bern, SwitzerlandDivision of Pediatric Hematology and Oncology, Department of Pediatrics, Inselspital Bern University Hospital, University of Bern, 3010 Bern, SwitzerlandDivision of Pediatric Hematology and Oncology, Department of Pediatrics, Inselspital Bern University Hospital, University of Bern, 3010 Bern, SwitzerlandDivision of Pediatric Hematology and Oncology, Department of Pediatrics, Inselspital Bern University Hospital, University of Bern, 3010 Bern, SwitzerlandPersonal and social resources may buffer the adverse effects of childhood cancer and its impact on cognition and quality of life. While childhood cancer survivors show domain-specific cognitive difficulties, little is known about their personal and social resources. We therefore investigated personal and social resources and their association with cognitive and quality-of-life outcomes in childhood cancer survivors. Seventy-eight survivors of childhood cancer of different etiologies (aged 7–16 years; ≥one year since treatment) and fifty-six healthy controls were included. Cognitive outcome was assessed by neuropsychological tests; personal and social resources, as well as health-related quality of life, were assessed by standardized questionnaires. In the social resource domain, peer integration was worse in survivors than in controls (<i>p</i><sub>uncorr</sub> < 0.04, <i>d</i> = 0.33). Personal resources and all other subscales of social resources did not significantly differ between survivors and controls. In survivors, the global resource score was significantly correlated with processing speed (<i>r</i> = 0.39, <i>p</i><sub>corr</sub> < 0.001) and quality of life (parent: <i>r</i> = 0.44; self-report: <i>r</i> = 0.46; <i>p</i><sub>scorr</sub> < 0.001). In controls, no association occurred between resources and cognitive outcome, and the correlation between the global resource score and quality of life did not withstand correction for multiple comparison (parent: <i>r</i> = 0.28; self-report: <i>r</i> = 0.40, <i>p</i><sub>suncorr</sub> < 0.001). After an adverse event such as childhood cancer, resources might play a particularly buffering role on cognitive performance and quality of life (when compared to the everyday life of healthy controls). This highlights the importance of interventions that strengthen the resources of children and their families, even years after cancer. Such resource-focused intervention could help to counteract long-term sequelae in cognitive outcomes and health-related quality of life.https://www.mdpi.com/2227-9067/9/7/936childhood cancer survivorssocial and personal resourcescognitive outcomehealth-related quality of life |
| spellingShingle | Valerie Siegwart Kirstin Schürch Valentin Benzing Jochen Roessler Regula Everts Personal and Social Resources Are Linked to Cognition and Health-Related Quality of Life in Childhood Cancer Survivors Children childhood cancer survivors social and personal resources cognitive outcome health-related quality of life |
| title | Personal and Social Resources Are Linked to Cognition and Health-Related Quality of Life in Childhood Cancer Survivors |
| title_full | Personal and Social Resources Are Linked to Cognition and Health-Related Quality of Life in Childhood Cancer Survivors |
| title_fullStr | Personal and Social Resources Are Linked to Cognition and Health-Related Quality of Life in Childhood Cancer Survivors |
| title_full_unstemmed | Personal and Social Resources Are Linked to Cognition and Health-Related Quality of Life in Childhood Cancer Survivors |
| title_short | Personal and Social Resources Are Linked to Cognition and Health-Related Quality of Life in Childhood Cancer Survivors |
| title_sort | personal and social resources are linked to cognition and health related quality of life in childhood cancer survivors |
| topic | childhood cancer survivors social and personal resources cognitive outcome health-related quality of life |
| url | https://www.mdpi.com/2227-9067/9/7/936 |
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