Long-read sequencing and de novo assembly of a Chinese genome
Short-read sequencing has inherent limitations in the characterisation of long repeat elements. Shi and Guo et al.combine single-molecule real-time sequencing and IrysChip to construct a Chinese reference genome that fills many gaps in the reference genome, and identify novel spliced genes.
Bibliographic Details
| Main Authors: |
Lingling Shi,
Yunfei Guo,
Chengliang Dong,
John Huddleston,
Hui Yang,
Xiaolu Han,
Aisi Fu,
Quan Li,
Na Li,
Siyi Gong,
Katherine E. Lintner,
Qiong Ding,
Zou Wang,
Jiang Hu,
Depeng Wang,
Feng Wang,
Lin Wang,
Gholson J. Lyon,
Yongtao Guan,
Yufeng Shen,
Oleg V. Evgrafov,
James A. Knowles,
Francoise Thibaud-Nissen,
Valerie Schneider,
Chack-Yung Yu,
Libing Zhou,
Evan E. Eichler,
Kwok-Fai So,
Kai Wang |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2016-06-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/ncomms12065
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