Epigenetic and non-epigenetic mode of SIRT1 action during oocyte meiosis progression

Epigenetic and non-epigenetic mode of SIRT1 action during oocyte meiosis progression

Abstract Background SIRT1 histone deacetylase acts on many epigenetic and non-epigenetic targets. It is thought that SIRT1 is involved in oocyte maturation; therefore, the importance of the ooplasmic SIRT1 pool for the further fate of mature oocytes has been strongly suggested. We hypothesised that...

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Bibliographic Details
Main Authors: Jan Nevoral, Lukas Landsmann, Miriam Stiavnicka, Petr Hosek, Jiri Moravec, Sarka Prokesova, Hedvika Rimnacova, Eliska Koutna, Pavel Klein, Kristyna Hoskova, Tereza Zalmanova, Tereza Fenclova, Jaroslav Petr, Milena Kralickova
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Journal of Animal Science and Biotechnology
Subjects:
Epigenetics
Histone code
In vitro maturation
Oocyte
SIRT1
Sirtuin 1
Online Access:http://link.springer.com/article/10.1186/s40104-019-0372-3

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