A Multi-Compartment Model of Glioma Response to Fractionated Radiation Therapy Parameterized via Time-Resolved Microscopy Data

A Multi-Compartment Model of Glioma Response to Fractionated Radiation Therapy Parameterized via Time-Resolved Microscopy Data

PurposeConventional radiobiology models, including the linear-quadratic model, do not explicitly account for the temporal effects of radiation, thereby making it difficult to make time-resolved predictions of tumor response to fractionated radiation. To overcome this limitation, we propose and valid...

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Bibliographic Details
Main Authors: Junyan Liu, David A. Hormuth, Jianchen Yang, Thomas E. Yankeelov
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Oncology
Subjects:
radiobiology
glioma
computational biology
mathematical modeling
oncology
brain cancer cell
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.811415/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.811415/full

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