Investigating a Lock-In Thermal Imaging Setup for the Detection and Characterization of Magnetic Nanoparticles
Magnetic hyperthermia treatments utilize the heat generated by magnetic nanoparticles stimulated by an alternating magnetic field. Therefore, analytical methods are required to precisely characterize the dissipated thermal energy and to evaluate potential amplifying or diminishing factors in order t...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-08-01
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| Series: | Nanomaterials |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-4991/10/9/1665 |
| _version_ | 1797555643735867392 |
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| author | Lukas Steinmetz Christoph Kirsch Christoph Geers Alke Petri-Fink Mathias Bonmarin |
| author_facet | Lukas Steinmetz Christoph Kirsch Christoph Geers Alke Petri-Fink Mathias Bonmarin |
| author_sort | Lukas Steinmetz |
| collection | DOAJ |
| description | Magnetic hyperthermia treatments utilize the heat generated by magnetic nanoparticles stimulated by an alternating magnetic field. Therefore, analytical methods are required to precisely characterize the dissipated thermal energy and to evaluate potential amplifying or diminishing factors in order to ensure optimal treatment conditions. Here, we present a lock-in thermal imaging setup specifically designed to thermally measure magnetic nanoparticles and we investigate theoretically how the various experimental parameters may influence the measurement. We compare two detection methods and highlight how an affordable microbolometer can achieve identical sensitivity with respect to a thermal camera-based system by adapting the measurement time. Furthermore, a numerical model is used to demonstrate the optimal stimulation frequency, the degree of nanomaterial heating power, preferential sample holder dimensions and the extent of heat losses to the environment. Using this model, we also revisit some technical assumptions and experimental results that previous studies have stated and suggest an optimal experimental configuration. |
| first_indexed | 2024-03-10T16:50:25Z |
| format | Article |
| id | doaj.art-0e2a6c7d10a3448bad3d76bb02826718 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-10T16:50:25Z |
| publishDate | 2020-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-0e2a6c7d10a3448bad3d76bb028267182023-11-20T11:19:14ZengMDPI AGNanomaterials2079-49912020-08-01109166510.3390/nano10091665Investigating a Lock-In Thermal Imaging Setup for the Detection and Characterization of Magnetic NanoparticlesLukas Steinmetz0Christoph Kirsch1Christoph Geers2Alke Petri-Fink3Mathias Bonmarin4Adolphe Merkle Institute, University of Fribourg, 1700 Fribourg, SwitzerlandInstitute of Computational Physics, School of Engineering, Zurich University of Applied Sciences, 8400 Winterthur, SwitzerlandAdolphe Merkle Institute, University of Fribourg, 1700 Fribourg, SwitzerlandAdolphe Merkle Institute, University of Fribourg, 1700 Fribourg, SwitzerlandInstitute of Computational Physics, School of Engineering, Zurich University of Applied Sciences, 8400 Winterthur, SwitzerlandMagnetic hyperthermia treatments utilize the heat generated by magnetic nanoparticles stimulated by an alternating magnetic field. Therefore, analytical methods are required to precisely characterize the dissipated thermal energy and to evaluate potential amplifying or diminishing factors in order to ensure optimal treatment conditions. Here, we present a lock-in thermal imaging setup specifically designed to thermally measure magnetic nanoparticles and we investigate theoretically how the various experimental parameters may influence the measurement. We compare two detection methods and highlight how an affordable microbolometer can achieve identical sensitivity with respect to a thermal camera-based system by adapting the measurement time. Furthermore, a numerical model is used to demonstrate the optimal stimulation frequency, the degree of nanomaterial heating power, preferential sample holder dimensions and the extent of heat losses to the environment. Using this model, we also revisit some technical assumptions and experimental results that previous studies have stated and suggest an optimal experimental configuration.https://www.mdpi.com/2079-4991/10/9/1665measurement instrumentthermal imagingmagnetic nanoparticleslock-in thermal imaging |
| spellingShingle | Lukas Steinmetz Christoph Kirsch Christoph Geers Alke Petri-Fink Mathias Bonmarin Investigating a Lock-In Thermal Imaging Setup for the Detection and Characterization of Magnetic Nanoparticles Nanomaterials measurement instrument thermal imaging magnetic nanoparticles lock-in thermal imaging |
| title | Investigating a Lock-In Thermal Imaging Setup for the Detection and Characterization of Magnetic Nanoparticles |
| title_full | Investigating a Lock-In Thermal Imaging Setup for the Detection and Characterization of Magnetic Nanoparticles |
| title_fullStr | Investigating a Lock-In Thermal Imaging Setup for the Detection and Characterization of Magnetic Nanoparticles |
| title_full_unstemmed | Investigating a Lock-In Thermal Imaging Setup for the Detection and Characterization of Magnetic Nanoparticles |
| title_short | Investigating a Lock-In Thermal Imaging Setup for the Detection and Characterization of Magnetic Nanoparticles |
| title_sort | investigating a lock in thermal imaging setup for the detection and characterization of magnetic nanoparticles |
| topic | measurement instrument thermal imaging magnetic nanoparticles lock-in thermal imaging |
| url | https://www.mdpi.com/2079-4991/10/9/1665 |
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