Priming with inflammatory cytokines is not a prerequisite to increase immune-suppressive effects and responsiveness of equine amniotic mesenchymal stromal cells

Priming with inflammatory cytokines is not a prerequisite to increase immune-suppressive effects and responsiveness of equine amniotic mesenchymal stromal cells

Abstract Background Equine amniotic mesenchymal stromal cells (AMSCs) and their conditioned medium (CM) were evaluated for their ability to inhibit in vitro proliferation of peripheral blood mononuclear cells (PBMCs) with and without priming. Additionally, AMSC immunogenicity was assessed by express...

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Bibliographic Details
Main Authors: Anna Lange-Consiglio, Pietro Romele, Marta Magatti, Antonietta Silini, Antonella Idda, Nicola Antonio Martino, Fausto Cremonesi, Ornella Parolini
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Stem Cell Research & Therapy
Subjects:
Equine
Amniotic stromal-derived cells
PBMC proliferation
Priming
Pro-inflammatory cytokines
Online Access:http://link.springer.com/article/10.1186/s13287-020-01611-z

Internet

http://link.springer.com/article/10.1186/s13287-020-01611-z

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