The repeatability of corneal topography measurements in severe Dry Eye disease
Abstract Background To determine the repeatability of corneal topography measurements in severe dry eye disease (DED). A comparison of corneal topography parameters between severe DED and healthy subjects was a secondary goal of this study. Methods Sixty-nine patients with severe DED and 46 healthy...
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| Format: | Article |
| Language: | English |
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BMC
2022-07-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-022-02534-4 |
| _version_ | 1818198294566797312 |
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| author | Soner Guven |
| author_facet | Soner Guven |
| author_sort | Soner Guven |
| collection | DOAJ |
| description | Abstract Background To determine the repeatability of corneal topography measurements in severe dry eye disease (DED). A comparison of corneal topography parameters between severe DED and healthy subjects was a secondary goal of this study. Methods Sixty-nine patients with severe DED and 46 healthy subjects were enrolled in the study. All participants underwent repeated corneal topography measurements with Pentacam (Oculus, Germany) within a half hour time. Both eyes of the participants were used in statistical analysis. A further subcategorization of severe DED patients was performed according to Ocular Surface Disease Index (OSDI) scores: 32–50, 51–70 and 71–100. The repeatability of corneal parameters was assessed with correlation coefficients (CC). Results The mean age of dry eye patients and healthy subjects were 40.8 ± 13.2 (17–66) and 39.8 ± 8.2 (18–61) years (p:0.604) respectively. No significant differences were found between severe DED and control groups according to analysed corneal parameters in both eyes (p:>0.05). All CCs were greater than 0.9 in severe DED group (p:<0.001). All CCs were also greater than 0.9 in severe DED patients among different OSDI groups (p:<0.001). Conclusions Corneal topography measurements are highly repeatable in severe DED with Pentacam. This is the first report about this topic. Nonetheless, further studies are needed with different topography devices for validation. |
| first_indexed | 2024-12-12T02:03:35Z |
| format | Article |
| id | doaj.art-0e2c7fc20bb449ed93f38b0d54b1a4e5 |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-12-12T02:03:35Z |
| publishDate | 2022-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-0e2c7fc20bb449ed93f38b0d54b1a4e52022-12-22T00:42:07ZengBMCBMC Ophthalmology1471-24152022-07-012211610.1186/s12886-022-02534-4The repeatability of corneal topography measurements in severe Dry Eye diseaseSoner Guven0Department of Ophthalmology, Kayseri City HospitalAbstract Background To determine the repeatability of corneal topography measurements in severe dry eye disease (DED). A comparison of corneal topography parameters between severe DED and healthy subjects was a secondary goal of this study. Methods Sixty-nine patients with severe DED and 46 healthy subjects were enrolled in the study. All participants underwent repeated corneal topography measurements with Pentacam (Oculus, Germany) within a half hour time. Both eyes of the participants were used in statistical analysis. A further subcategorization of severe DED patients was performed according to Ocular Surface Disease Index (OSDI) scores: 32–50, 51–70 and 71–100. The repeatability of corneal parameters was assessed with correlation coefficients (CC). Results The mean age of dry eye patients and healthy subjects were 40.8 ± 13.2 (17–66) and 39.8 ± 8.2 (18–61) years (p:0.604) respectively. No significant differences were found between severe DED and control groups according to analysed corneal parameters in both eyes (p:>0.05). All CCs were greater than 0.9 in severe DED group (p:<0.001). All CCs were also greater than 0.9 in severe DED patients among different OSDI groups (p:<0.001). Conclusions Corneal topography measurements are highly repeatable in severe DED with Pentacam. This is the first report about this topic. Nonetheless, further studies are needed with different topography devices for validation.https://doi.org/10.1186/s12886-022-02534-4Corneal topographyRepeatabilityPentacamSevere dry eye disease |
| spellingShingle | Soner Guven The repeatability of corneal topography measurements in severe Dry Eye disease BMC Ophthalmology Corneal topography Repeatability Pentacam Severe dry eye disease |
| title | The repeatability of corneal topography measurements in severe Dry Eye disease |
| title_full | The repeatability of corneal topography measurements in severe Dry Eye disease |
| title_fullStr | The repeatability of corneal topography measurements in severe Dry Eye disease |
| title_full_unstemmed | The repeatability of corneal topography measurements in severe Dry Eye disease |
| title_short | The repeatability of corneal topography measurements in severe Dry Eye disease |
| title_sort | repeatability of corneal topography measurements in severe dry eye disease |
| topic | Corneal topography Repeatability Pentacam Severe dry eye disease |
| url | https://doi.org/10.1186/s12886-022-02534-4 |
| work_keys_str_mv | AT sonerguven therepeatabilityofcornealtopographymeasurementsinseveredryeyedisease AT sonerguven repeatabilityofcornealtopographymeasurementsinseveredryeyedisease |