The translational significance of epithelial‐mesenchymal transition in head and neck cancer
Abstract Positive markers of epithelial‐mesenchymal transition (EMT) in head and neck cancers complicate clinical management and are associated with reduced survival. We discuss recent translational discoveries in EMT and suggest additional actionable molecular pathways, biomarkers, and clinical age...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-12-01
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| Series: | Clinical and Translational Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40169-014-0039-9 |
| _version_ | 1818851396047339520 |
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| author | Christian A Graves Fadi F Abboodi Swati Tomar James Wells Lucia Pirisi |
| author_facet | Christian A Graves Fadi F Abboodi Swati Tomar James Wells Lucia Pirisi |
| author_sort | Christian A Graves |
| collection | DOAJ |
| description | Abstract Positive markers of epithelial‐mesenchymal transition (EMT) in head and neck cancers complicate clinical management and are associated with reduced survival. We discuss recent translational discoveries in EMT and suggest additional actionable molecular pathways, biomarkers, and clinical agents. |
| first_indexed | 2024-12-19T07:04:21Z |
| format | Article |
| id | doaj.art-0e2ed2e98d58449d97e5630414e3da51 |
| institution | Directory Open Access Journal |
| issn | 2001-1326 |
| language | English |
| last_indexed | 2024-12-19T07:04:21Z |
| publishDate | 2014-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical and Translational Medicine |
| spelling | doaj.art-0e2ed2e98d58449d97e5630414e3da512022-12-21T20:31:18ZengWileyClinical and Translational Medicine2001-13262014-12-0131n/an/a10.1186/s40169-014-0039-9The translational significance of epithelial‐mesenchymal transition in head and neck cancerChristian A Graves0Fadi F Abboodi1Swati Tomar2James Wells3Lucia Pirisi4Department of PathologyMicrobiology & ImmunologyUniversity of South Carolina School of MedicineBldg. 1 Room B43 6439 Garners Ferry Rd29208ColumbiaSCUSADepartment of PathologyMicrobiology & ImmunologyUniversity of South Carolina School of MedicineBldg. 1 Room B43 6439 Garners Ferry Rd29208ColumbiaSCUSADepartment of PathologyMicrobiology & ImmunologyUniversity of South Carolina School of MedicineBldg. 1 Room B43 6439 Garners Ferry Rd29208ColumbiaSCUSADepartment of Head and Neck SurgeryWm. Jennings Dorn VA Medical Center29208ColumbiaSCUSADepartment of PathologyMicrobiology & ImmunologyUniversity of South Carolina School of MedicineBldg. 1 Room B43 6439 Garners Ferry Rd29208ColumbiaSCUSAAbstract Positive markers of epithelial‐mesenchymal transition (EMT) in head and neck cancers complicate clinical management and are associated with reduced survival. We discuss recent translational discoveries in EMT and suggest additional actionable molecular pathways, biomarkers, and clinical agents.https://doi.org/10.1186/s40169-014-0039-9EMT head and Neck cancerSnailSlugBiomarkersTGF beta and Head and Neck cancerEMT and HPV |
| spellingShingle | Christian A Graves Fadi F Abboodi Swati Tomar James Wells Lucia Pirisi The translational significance of epithelial‐mesenchymal transition in head and neck cancer Clinical and Translational Medicine EMT head and Neck cancer Snail Slug Biomarkers TGF beta and Head and Neck cancer EMT and HPV |
| title | The translational significance of epithelial‐mesenchymal transition in head and neck cancer |
| title_full | The translational significance of epithelial‐mesenchymal transition in head and neck cancer |
| title_fullStr | The translational significance of epithelial‐mesenchymal transition in head and neck cancer |
| title_full_unstemmed | The translational significance of epithelial‐mesenchymal transition in head and neck cancer |
| title_short | The translational significance of epithelial‐mesenchymal transition in head and neck cancer |
| title_sort | translational significance of epithelial mesenchymal transition in head and neck cancer |
| topic | EMT head and Neck cancer Snail Slug Biomarkers TGF beta and Head and Neck cancer EMT and HPV |
| url | https://doi.org/10.1186/s40169-014-0039-9 |
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