Middle East Medicinal Plants in the Treatment of Diabetes: A Review

Diabetes is a global health problem, and the number of diabetic patients is in continuous rise. Conventional antidiabetic therapies are associated with high costs and limited efficiency. The use of traditional medicine and plant extracts to treat diabetes is gaining high popularity in many countries...

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Main Authors: Alaa M. Abu-Odeh, Wamidh H. Talib
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/3/742
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author Alaa M. Abu-Odeh
Wamidh H. Talib
author_facet Alaa M. Abu-Odeh
Wamidh H. Talib
author_sort Alaa M. Abu-Odeh
collection DOAJ
description Diabetes is a global health problem, and the number of diabetic patients is in continuous rise. Conventional antidiabetic therapies are associated with high costs and limited efficiency. The use of traditional medicine and plant extracts to treat diabetes is gaining high popularity in many countries. Countries in the Middle East region have a long history of using herbal medicine to treat different diseases, including diabetes. In this review, we compiled and summarized all the in vivo and in vitro studies conducted for plants with potential antidiabetic activity in the Middle East region. Plants of the Asteraceae and Lamiaceae families are the most investigated. It is hoped that this review will contribute scientifically to evidence the ethnobotanical use of medicinal plants as antidiabetic agents. Work has to be done to define tagetes, mechanism of action and the compound responsible for activity. In addition, safety and pharmacokinetic parameters should be investigated.
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spelling doaj.art-0e3655176098419ebaf8d087144471e22023-12-03T11:50:05ZengMDPI AGMolecules1420-30492021-01-0126374210.3390/molecules26030742Middle East Medicinal Plants in the Treatment of Diabetes: A ReviewAlaa M. Abu-Odeh0Wamidh H. Talib1Department of pharmaceutical sciences, Faculty of Pharmacy, The University of Jordan, Amman 11942, JordanDepartment of Clinical Pharmacy and Therapeutics, Applied Science Private University, Amman 11931-166, JordanDiabetes is a global health problem, and the number of diabetic patients is in continuous rise. Conventional antidiabetic therapies are associated with high costs and limited efficiency. The use of traditional medicine and plant extracts to treat diabetes is gaining high popularity in many countries. Countries in the Middle East region have a long history of using herbal medicine to treat different diseases, including diabetes. In this review, we compiled and summarized all the in vivo and in vitro studies conducted for plants with potential antidiabetic activity in the Middle East region. Plants of the Asteraceae and Lamiaceae families are the most investigated. It is hoped that this review will contribute scientifically to evidence the ethnobotanical use of medicinal plants as antidiabetic agents. Work has to be done to define tagetes, mechanism of action and the compound responsible for activity. In addition, safety and pharmacokinetic parameters should be investigated.https://www.mdpi.com/1420-3049/26/3/742antidiabetic plantsnatural productshyperglycemiaplant extracts
spellingShingle Alaa M. Abu-Odeh
Wamidh H. Talib
Middle East Medicinal Plants in the Treatment of Diabetes: A Review
Molecules
antidiabetic plants
natural products
hyperglycemia
plant extracts
title Middle East Medicinal Plants in the Treatment of Diabetes: A Review
title_full Middle East Medicinal Plants in the Treatment of Diabetes: A Review
title_fullStr Middle East Medicinal Plants in the Treatment of Diabetes: A Review
title_full_unstemmed Middle East Medicinal Plants in the Treatment of Diabetes: A Review
title_short Middle East Medicinal Plants in the Treatment of Diabetes: A Review
title_sort middle east medicinal plants in the treatment of diabetes a review
topic antidiabetic plants
natural products
hyperglycemia
plant extracts
url https://www.mdpi.com/1420-3049/26/3/742
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