Managing Uncertainty in Biomedical Innovation from Below. Exploring Tensions and Contradictions in Oncology and Pregnancy Cases

The contribution originates from Track 1, “Genetics and biomedical innovation: Between risky and promising scenarios”, held within the VIII STS Italia conference. The session was intended to promote reflection on the implications of the latest innovations in genetic research and molecular biology fo...

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Main Authors: Barbara Morsello, Veronica Moretti
Format: Article
Language:English
Published: University of Bologna – Dipartimento di Filosofia e Comunicazione 2022-03-01
Series:Tecnoscienza
Subjects:
Online Access:https://tecnoscienza.unibo.it/article/view/17511
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author Barbara Morsello
Veronica Moretti
author_facet Barbara Morsello
Veronica Moretti
author_sort Barbara Morsello
collection DOAJ
description The contribution originates from Track 1, “Genetics and biomedical innovation: Between risky and promising scenarios”, held within the VIII STS Italia conference. The session was intended to promote reflection on the implications of the latest innovations in genetic research and molecular biology for the formation of new care practices, as well as new surveillance and risk management. The objective of the paper is to highlights the contradictions and ambivalence that may rise from biomedical innovation through analysing two specific cases: 1) off-label practice in the context of rare disease in oncology and 2) pre-natal screening technology and surveillance practices. In both cases, these biomedical innovations, although very promising, produced high uncertainty, and the technologies and/or processes developed to cope with the “unknown” were challenging. However, at the same time, tensions and contradictions were observed that originated unexpected practices “from below”. In particular, the following section is focused on the ambivalence that has increasingly taken root in the management of risks related to health with respect to individual contributions and to research and scientific work practices.
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spelling doaj.art-0e36d54e977d4170ad479f9b974691152024-01-22T10:27:43ZengUniversity of Bologna – Dipartimento di Filosofia e ComunicazioneTecnoscienza2038-34602022-03-01122496010.6092/issn.2038-3460/1751115870Managing Uncertainty in Biomedical Innovation from Below. Exploring Tensions and Contradictions in Oncology and Pregnancy CasesBarbara Morsello0Veronica Moretti1University of PaduaUniversity of BolognaThe contribution originates from Track 1, “Genetics and biomedical innovation: Between risky and promising scenarios”, held within the VIII STS Italia conference. The session was intended to promote reflection on the implications of the latest innovations in genetic research and molecular biology for the formation of new care practices, as well as new surveillance and risk management. The objective of the paper is to highlights the contradictions and ambivalence that may rise from biomedical innovation through analysing two specific cases: 1) off-label practice in the context of rare disease in oncology and 2) pre-natal screening technology and surveillance practices. In both cases, these biomedical innovations, although very promising, produced high uncertainty, and the technologies and/or processes developed to cope with the “unknown” were challenging. However, at the same time, tensions and contradictions were observed that originated unexpected practices “from below”. In particular, the following section is focused on the ambivalence that has increasingly taken root in the management of risks related to health with respect to individual contributions and to research and scientific work practices.https://tecnoscienza.unibo.it/article/view/17511biomedical researchgenomicsdigital pregnancyself-surveillanceoff-label
spellingShingle Barbara Morsello
Veronica Moretti
Managing Uncertainty in Biomedical Innovation from Below. Exploring Tensions and Contradictions in Oncology and Pregnancy Cases
Tecnoscienza
biomedical research
genomics
digital pregnancy
self-surveillance
off-label
title Managing Uncertainty in Biomedical Innovation from Below. Exploring Tensions and Contradictions in Oncology and Pregnancy Cases
title_full Managing Uncertainty in Biomedical Innovation from Below. Exploring Tensions and Contradictions in Oncology and Pregnancy Cases
title_fullStr Managing Uncertainty in Biomedical Innovation from Below. Exploring Tensions and Contradictions in Oncology and Pregnancy Cases
title_full_unstemmed Managing Uncertainty in Biomedical Innovation from Below. Exploring Tensions and Contradictions in Oncology and Pregnancy Cases
title_short Managing Uncertainty in Biomedical Innovation from Below. Exploring Tensions and Contradictions in Oncology and Pregnancy Cases
title_sort managing uncertainty in biomedical innovation from below exploring tensions and contradictions in oncology and pregnancy cases
topic biomedical research
genomics
digital pregnancy
self-surveillance
off-label
url https://tecnoscienza.unibo.it/article/view/17511
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AT veronicamoretti managinguncertaintyinbiomedicalinnovationfrombelowexploringtensionsandcontradictionsinoncologyandpregnancycases