Epidemiological Study of Sepsis in China: Protocol of a Cross-sectional Survey
Background: Sepsis is the leading cause of death among critically ill patients. Herein, we conducted a national survey to provide data on epidemiology and treatment of sepsis in the clinical practice in China, which has no detailed epidemiological data available on sepsis. Methods: This was a prospe...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer
2016-01-01
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| Series: | Chinese Medical Journal |
| Subjects: | |
| Online Access: | http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=24;spage=2967;epage=2973;aulast=Yang |
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| author | Yi Yang Jian-Feng Xie Kai-Jiang Yu Chen Yao Jian-Guo Li Xiang-Dong Guan Jing Yan Xiao-Chun Ma Yan Kang Cong-Shan Yang Xiao-Qing Yao Hong-Cai Shang Hai-Bo Qiu for CHESS Study Investigators |
| author_facet | Yi Yang Jian-Feng Xie Kai-Jiang Yu Chen Yao Jian-Guo Li Xiang-Dong Guan Jing Yan Xiao-Chun Ma Yan Kang Cong-Shan Yang Xiao-Qing Yao Hong-Cai Shang Hai-Bo Qiu for CHESS Study Investigators |
| author_sort | Yi Yang |
| collection | DOAJ |
| description | Background: Sepsis is the leading cause of death among critically ill patients. Herein, we conducted a national survey to provide data on epidemiology and treatment of sepsis in the clinical practice in China, which has no detailed epidemiological data available on sepsis.
Methods: This was a prospective cross-sectional survey from December 1, 2015 to January 31, 2016 in all provinces/municipalities of the mainland of China. The primary outcome of this study was the incidence of sepsis, and the secondary outcome was its etiology in China. Patients with sepsis admitted to the Intensive Care Units were included in this study. The demographic, physiological, bacteriological, and therapeutic data of these patients were recorded. The incidence of sepsis was estimated using the data from the sixth census in China, reported by the Chinese National Health and Family Planning Commission and the National Bureau of Statistics as the standard population. The independent risk factors for increased mortality from sepsis were calculated.
Conclusions: This study indicated the incidence and outcome of sepsis in China. It also showed the most common etiology of different sites and types of infection, which could guide empiric antibiotic therapy. Moreover, it provided information on the independent risk factors for increased mortality due to sepsis. The findings provide evidence to guide clinical management and may help improve the outcome in septic patients.
Trial Registration: ClinicalTrials.gov, NCT02448472; https://clinicaltrials.gov/show/NCT02448472. |
| first_indexed | 2024-12-13T15:28:49Z |
| format | Article |
| id | doaj.art-0e392702bad94693bbab2c1208fa060c |
| institution | Directory Open Access Journal |
| issn | 0366-6999 |
| language | English |
| last_indexed | 2024-12-13T15:28:49Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Chinese Medical Journal |
| spelling | doaj.art-0e392702bad94693bbab2c1208fa060c2022-12-21T23:40:16ZengWolters KluwerChinese Medical Journal0366-69992016-01-01129242967297310.4103/0366-6999.195474Epidemiological Study of Sepsis in China: Protocol of a Cross-sectional SurveyYi YangJian-Feng XieKai-Jiang YuChen YaoJian-Guo LiXiang-Dong GuanJing YanXiao-Chun MaYan KangCong-Shan YangXiao-Qing YaoHong-Cai ShangHai-Bo Qiufor CHESS Study InvestigatorsBackground: Sepsis is the leading cause of death among critically ill patients. Herein, we conducted a national survey to provide data on epidemiology and treatment of sepsis in the clinical practice in China, which has no detailed epidemiological data available on sepsis. Methods: This was a prospective cross-sectional survey from December 1, 2015 to January 31, 2016 in all provinces/municipalities of the mainland of China. The primary outcome of this study was the incidence of sepsis, and the secondary outcome was its etiology in China. Patients with sepsis admitted to the Intensive Care Units were included in this study. The demographic, physiological, bacteriological, and therapeutic data of these patients were recorded. The incidence of sepsis was estimated using the data from the sixth census in China, reported by the Chinese National Health and Family Planning Commission and the National Bureau of Statistics as the standard population. The independent risk factors for increased mortality from sepsis were calculated. Conclusions: This study indicated the incidence and outcome of sepsis in China. It also showed the most common etiology of different sites and types of infection, which could guide empiric antibiotic therapy. Moreover, it provided information on the independent risk factors for increased mortality due to sepsis. The findings provide evidence to guide clinical management and may help improve the outcome in septic patients. Trial Registration: ClinicalTrials.gov, NCT02448472; https://clinicaltrials.gov/show/NCT02448472.http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=24;spage=2967;epage=2973;aulast=YangEpidemiology; Incidence; National Survey; Outcome; Sepsis |
| spellingShingle | Yi Yang Jian-Feng Xie Kai-Jiang Yu Chen Yao Jian-Guo Li Xiang-Dong Guan Jing Yan Xiao-Chun Ma Yan Kang Cong-Shan Yang Xiao-Qing Yao Hong-Cai Shang Hai-Bo Qiu for CHESS Study Investigators Epidemiological Study of Sepsis in China: Protocol of a Cross-sectional Survey Chinese Medical Journal Epidemiology; Incidence; National Survey; Outcome; Sepsis |
| title | Epidemiological Study of Sepsis in China: Protocol of a Cross-sectional Survey |
| title_full | Epidemiological Study of Sepsis in China: Protocol of a Cross-sectional Survey |
| title_fullStr | Epidemiological Study of Sepsis in China: Protocol of a Cross-sectional Survey |
| title_full_unstemmed | Epidemiological Study of Sepsis in China: Protocol of a Cross-sectional Survey |
| title_short | Epidemiological Study of Sepsis in China: Protocol of a Cross-sectional Survey |
| title_sort | epidemiological study of sepsis in china protocol of a cross sectional survey |
| topic | Epidemiology; Incidence; National Survey; Outcome; Sepsis |
| url | http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=24;spage=2967;epage=2973;aulast=Yang |
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