Management of severe factor XI deficiency in pregnancy: A case report
Factor XI (FXI) deficiency is one of the rarest coagulation disorders with a frequency of 1:1,000,000. A 30-year-old woman, diagnosed with FXI deficiency at the age of 4, was admitted to our maternity service at 25 weeks of gestation. The patient had no history of hemorrhage or abnormal bleeding, an...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2024-03-01
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| Series: | SAGE Open Medical Case Reports |
| Online Access: | https://doi.org/10.1177/2050313X241241196 |
| _version_ | 1797257655737122816 |
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| author | Fatima El Hassouni Asmae Bentaleb Sofia Lahbabi Rajae Tachinante Mohamed Elkhorassani Mounia Yousfi |
| author_facet | Fatima El Hassouni Asmae Bentaleb Sofia Lahbabi Rajae Tachinante Mohamed Elkhorassani Mounia Yousfi |
| author_sort | Fatima El Hassouni |
| collection | DOAJ |
| description | Factor XI (FXI) deficiency is one of the rarest coagulation disorders with a frequency of 1:1,000,000. A 30-year-old woman, diagnosed with FXI deficiency at the age of 4, was admitted to our maternity service at 25 weeks of gestation. The patient had no history of hemorrhage or abnormal bleeding, and the clinical examination was unremarkable. Antenatal care was also normal. The parturient was admitted in early labor at 38 weeks of gestation. Despite the absence of clinical hemorrhagic syndrome, a transfusion of fresh frozen plasma combined with tranexamic acid was initiated once the active stage of labor was started. Management of FXI deficiency in pregnant women is a challenge due to its unpredictable bleeding tendency, and careful planning and knowledge of appropriate hemostatic management is pivotal for their care. |
| first_indexed | 2024-04-24T22:41:06Z |
| format | Article |
| id | doaj.art-0e3985cc1b33470186e3007bcbee5ab5 |
| institution | Directory Open Access Journal |
| issn | 2050-313X |
| language | English |
| last_indexed | 2024-04-24T22:41:06Z |
| publishDate | 2024-03-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | SAGE Open Medical Case Reports |
| spelling | doaj.art-0e3985cc1b33470186e3007bcbee5ab52024-03-19T01:03:24ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2024-03-011210.1177/2050313X241241196Management of severe factor XI deficiency in pregnancy: A case reportFatima El Hassouni0Asmae Bentaleb1Sofia Lahbabi2Rajae Tachinante3Mohamed Elkhorassani4Mounia Yousfi5Department of Obstetrics and Gynaecology, Oncology and High Risk Pregnancies, Maternity Hospital Souissi, Ibn Sina Teaching Hospital, Rabat, MoroccoDepartment of Obstetrics and Gynaecology, Oncology and High Risk Pregnancies, Maternity Hospital Souissi, Ibn Sina Teaching Hospital, Rabat, MoroccoDepartment of Intensive Care Unit, Maternity Hospital IBN SINA, Rabat, MoroccoDepartment of Intensive Care Unit, Maternity Hospital IBN SINA, Rabat, MoroccoHaemophilia Treatment Centre, Haematology and Oncology Unit, Mohammed V University Hospital, Rabat, MoroccoDepartment of Obstetrics and Gynaecology, Oncology and High Risk Pregnancies, Maternity Hospital Souissi, Ibn Sina Teaching Hospital, Rabat, MoroccoFactor XI (FXI) deficiency is one of the rarest coagulation disorders with a frequency of 1:1,000,000. A 30-year-old woman, diagnosed with FXI deficiency at the age of 4, was admitted to our maternity service at 25 weeks of gestation. The patient had no history of hemorrhage or abnormal bleeding, and the clinical examination was unremarkable. Antenatal care was also normal. The parturient was admitted in early labor at 38 weeks of gestation. Despite the absence of clinical hemorrhagic syndrome, a transfusion of fresh frozen plasma combined with tranexamic acid was initiated once the active stage of labor was started. Management of FXI deficiency in pregnant women is a challenge due to its unpredictable bleeding tendency, and careful planning and knowledge of appropriate hemostatic management is pivotal for their care.https://doi.org/10.1177/2050313X241241196 |
| spellingShingle | Fatima El Hassouni Asmae Bentaleb Sofia Lahbabi Rajae Tachinante Mohamed Elkhorassani Mounia Yousfi Management of severe factor XI deficiency in pregnancy: A case report SAGE Open Medical Case Reports |
| title | Management of severe factor XI deficiency in pregnancy: A case report |
| title_full | Management of severe factor XI deficiency in pregnancy: A case report |
| title_fullStr | Management of severe factor XI deficiency in pregnancy: A case report |
| title_full_unstemmed | Management of severe factor XI deficiency in pregnancy: A case report |
| title_short | Management of severe factor XI deficiency in pregnancy: A case report |
| title_sort | management of severe factor xi deficiency in pregnancy a case report |
| url | https://doi.org/10.1177/2050313X241241196 |
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