Super Enhancer Profiles Identify Key Cell Identity Genes During Differentiation From Embryonic Stem Cells to Trophoblast Stem Cells Super Enhencers in Trophoblast Differentiation

Super Enhancer Profiles Identify Key Cell Identity Genes During Differentiation From Embryonic Stem Cells to Trophoblast Stem Cells Super Enhencers in Trophoblast Differentiation

Trophoblast stem cells (TSCs) are derived from blastocysts and the extra-embryonic ectoderm (ExE) of post-implantation embryos and play a significant role in fetal development, but the roles that TSCs play in the earlier status of fetal diseases need further exploration. Super enhancers (SEs) are de...

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Bibliographic Details
Main Authors: Rongpu Jia, Yu Gao, Song Guo, Si Li, Liangji Zhou, Chenyu Gou, Yijuan Huang, Meiqiong Fan, Yuanqiu Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Genetics
Subjects:
trophoblast stem cell
embryonic stem cell
super enhancer
H3K27ac
H3K4me1
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.762529/full

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