Genetic variants of MUC4 are associated with susceptibility to and mortality of colorectal cancer and exhibit synergistic effects with LDL-C levels.
As a disease with high mortality and prevalence rates worldwide, colorectal cancer (CRC) has been thoroughly investigated. Mucins are involved in the induction of CRC and the regulation of intestinal homeostasis but a member of the mucin gene family MUC4 has a controversial role in CRC. MUC4 has bee...
Main Authors: | Min Jung Kwon, Jeong Yong Lee, Eo Jin Kim, Eun Ju Ko, Chang Soo Ryu, Hye Jung Cho, Hak Hoon Jun, Jong Woo Kim, Nam Keun Kim |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2023-01-01
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Series: | PLoS ONE |
Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0287768&type=printable |
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