New uses and formulations of glucagon for hypoglycaemia
Hypoglycaemia is the more frequent complication of insulin therapy and the main barrier to tight glycaemic control. Injectable glucagon and oral intake of carbohydrates are the recommended treatments for severe and non-severe hypoglycaemia episodes, respectively. Nasal glucagon is currently being de...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BioExcel Publishing Ltd
2019-07-01
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| Series: | Drugs in Context |
| Subjects: | |
| Online Access: | https://www.drugsincontext.com/new-uses-and-formulations-of-glucagon-for-hypoglycaemia/ |
| _version_ | 1818313043164004352 |
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| author | Pilar I Beato-Víbora Francisco J Arroyo-Díez |
| author_facet | Pilar I Beato-Víbora Francisco J Arroyo-Díez |
| author_sort | Pilar I Beato-Víbora |
| collection | DOAJ |
| description | Hypoglycaemia is the more frequent complication of insulin therapy and the main barrier to tight glycaemic control. Injectable glucagon and oral intake of carbohydrates are the recommended treatments for severe and non-severe hypoglycaemia episodes, respectively. Nasal glucagon is currently being developed as a ready-to-use device, to simplify severe hypoglycaemia rescue. Stable forms of liquid glucagon could open the field for different approaches for mild to moderate hypoglycaemia treatment, such as mini-doses of glucagon or continuous subcutaneous glucagon infusion as a part of dual-hormone closed-loop systems. Pharmaceutical companies are developing stable forms of native glucagon or glucagon analogues for that purpose. |
| first_indexed | 2024-12-13T08:27:28Z |
| format | Article |
| id | doaj.art-0e413bd0ca6f400cb5c2abd69bc67762 |
| institution | Directory Open Access Journal |
| issn | 1740-4398 1740-4398 |
| language | English |
| last_indexed | 2024-12-13T08:27:28Z |
| publishDate | 2019-07-01 |
| publisher | BioExcel Publishing Ltd |
| record_format | Article |
| series | Drugs in Context |
| spelling | doaj.art-0e413bd0ca6f400cb5c2abd69bc677622022-12-21T23:53:51ZengBioExcel Publishing LtdDrugs in Context1740-43981740-43982019-07-01811010.7573/dic.212599New uses and formulations of glucagon for hypoglycaemiaPilar I Beato-Víbora0Francisco J Arroyo-Díez1Department of Endocrinology and Nutrition, Department of Paediatrics, Badajoz University Hospital, Badajoz, SpainDepartment of Endocrinology and Nutrition, Department of Paediatrics, Badajoz University Hospital, Badajoz, SpainHypoglycaemia is the more frequent complication of insulin therapy and the main barrier to tight glycaemic control. Injectable glucagon and oral intake of carbohydrates are the recommended treatments for severe and non-severe hypoglycaemia episodes, respectively. Nasal glucagon is currently being developed as a ready-to-use device, to simplify severe hypoglycaemia rescue. Stable forms of liquid glucagon could open the field for different approaches for mild to moderate hypoglycaemia treatment, such as mini-doses of glucagon or continuous subcutaneous glucagon infusion as a part of dual-hormone closed-loop systems. Pharmaceutical companies are developing stable forms of native glucagon or glucagon analogues for that purpose.https://www.drugsincontext.com/new-uses-and-formulations-of-glucagon-for-hypoglycaemia/type 1 diabetesglucagonnasal glucagonhypoglycaemiadual-hormone artificial pancreasexercisemini-dose glucagoninjectable glucagon |
| spellingShingle | Pilar I Beato-Víbora Francisco J Arroyo-Díez New uses and formulations of glucagon for hypoglycaemia Drugs in Context type 1 diabetes glucagon nasal glucagon hypoglycaemia dual-hormone artificial pancreas exercise mini-dose glucagon injectable glucagon |
| title | New uses and formulations of glucagon for hypoglycaemia |
| title_full | New uses and formulations of glucagon for hypoglycaemia |
| title_fullStr | New uses and formulations of glucagon for hypoglycaemia |
| title_full_unstemmed | New uses and formulations of glucagon for hypoglycaemia |
| title_short | New uses and formulations of glucagon for hypoglycaemia |
| title_sort | new uses and formulations of glucagon for hypoglycaemia |
| topic | type 1 diabetes glucagon nasal glucagon hypoglycaemia dual-hormone artificial pancreas exercise mini-dose glucagon injectable glucagon |
| url | https://www.drugsincontext.com/new-uses-and-formulations-of-glucagon-for-hypoglycaemia/ |
| work_keys_str_mv | AT pilaribeatovibora newusesandformulationsofglucagonforhypoglycaemia AT franciscojarroyodiez newusesandformulationsofglucagonforhypoglycaemia |