Dual Role for Inflammasome Sensors NLRP1 and NLRP3 in Murine Resistance to <named-content content-type="genus-species">Toxoplasma gondii</named-content>

Dual Role for Inflammasome Sensors NLRP1 and NLRP3 in Murine Resistance to <named-content content-type="genus-species">Toxoplasma gondii</named-content>

ABSTRACT Induction of immunity that limits Toxoplasma gondii infection in mice is critically dependent on the activation of the innate immune response. In this study, we investigated the role of cytoplasmic nucleotide-binding domain and leucine-rich repeat containing a pyrin domain (NLRP) inflammaso...

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Main Authors: Gezahegn Gorfu, Kimberly M. Cirelli, Mariane B. Melo, Katrin Mayer-Barber, Devorah Crown, Beverly H. Koller, Seth Masters, Alan Sher, Stephen H. Leppla, Mahtab Moayeri, Jeroen P. J. Saeij, Michael E. Grigg
Format: Article
Language:English
Published: American Society for Microbiology 2014-02-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01117-13

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