Antidepressive and antinociceptive effects of ethanolic extract and fruticuline A from Salvia lachnostachys Benth leaves on rodents.

Antidepressive and antinociceptive effects of ethanolic extract and fruticuline A from Salvia lachnostachys Benth leaves on rodents.

OBJECTIVES:This study investigated the antidepressant and antinociceptive effects of ethanolic extract (SLEE) and pure fruticuline A obtained from Salvia lachnostachys leaves on rats and mice. METHODS:In this study, SLEE (100 mg/kg, p.o. route) was evaluated for its effects on spared nerve injury (S...

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Main Authors: Joyce Alencar Santos, Ana Claudia Piccinelli, Maira Dante Formagio, Cristhian Santos Oliveira, Elide Pereira Dos Santos, Maria Élida Alves Stefanello, Ubirajara Lanza Junior, Rodrigo Juliano Oliveira, Mário Mateus Sugizaki, Cândida Aparecida Leite Kassuya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5319787?pdf=render

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