Therapeutic targets for inflammatory bowel disease: proteome-wide Mendelian randomization and colocalization analysesResearch in context

Therapeutic targets for inflammatory bowel disease: proteome-wide Mendelian randomization and colocalization analysesResearch in context

Summary: Background: Identifying new drug targets for inflammatory bowel disease (IBD) is urgently needed. The proteome is a major source of therapeutic targets. We conducted a proteome-wide Mendelian randomization (MR) and colocalization analyses to identify possible targets for IBD. Methods: Summ...

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Bibliographic Details
Main Authors: Jie Chen, Fengzhe Xu, Xixian Ruan, Jing Sun, Yao Zhang, Han Zhang, Jianhui Zhao, Jie Zheng, Susanna C. Larsson, Xiaoyan Wang, Xue Li, Shuai Yuan
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:EBioMedicine
Subjects:
Inflammatory bowel disease
Mendelian randomization
Protein
Therapeutic target
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423000592

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