Bibliometric analysis of global research on the role of apolipoprotein E in Alzheimer's disease
Alzheimer's disease (AD) has attracted considerable attention from the public and scientific researchers, leading to a rapid growth in relevant research on this disorder in the last 10 years. The present study aimed to conduct a bibliometric analysis to elucidate the trends of global research o...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-07-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023051952 |
| _version_ | 1797771409686003712 |
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| author | Zhanzhang Wang Xiuqing Zhu Yuguan Wen Dewei Shang |
| author_facet | Zhanzhang Wang Xiuqing Zhu Yuguan Wen Dewei Shang |
| author_sort | Zhanzhang Wang |
| collection | DOAJ |
| description | Alzheimer's disease (AD) has attracted considerable attention from the public and scientific researchers, leading to a rapid growth in relevant research on this disorder in the last 10 years. The present study aimed to conduct a bibliometric analysis to elucidate the trends of global research on the role of apolipoprotein E in AD in the past decade. Three bibliometric software (CiteSpace, VOSviewer, and R Bibliometrix) were used to analyze the active journals, countries/regions, institutes, authors, co-cited references, and keywords in this field. The USA was the most influential country, and the University of California was the most productive institute. Zetterberg H contributed the highest number of publications, and Petersen RC was the most cited author in this field. On the basis of the co-cited reference analysis, knowledge base on biomarkers, risk factors, and mechanisms were updated in the past decade. Current research hotspots are shifting to tau-related mechanisms and identification of genetic risk factors. Our study provides insights into the developing knowledge base and trends related to research on apolipoprotein E in AD, which may provide new directions for further research in this field. |
| first_indexed | 2024-03-12T21:37:08Z |
| format | Article |
| id | doaj.art-0e4d969050544dd48bebbcc24ebcc0d3 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-12T21:37:08Z |
| publishDate | 2023-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-0e4d969050544dd48bebbcc24ebcc0d32023-07-27T05:58:10ZengElsevierHeliyon2405-84402023-07-0197e17987Bibliometric analysis of global research on the role of apolipoprotein E in Alzheimer's diseaseZhanzhang Wang0Xiuqing Zhu1Yuguan Wen2Dewei Shang3Department of Pharmacy, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China; Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, ChinaDepartment of Pharmacy, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China; Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, ChinaDepartment of Pharmacy, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China; Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China; Corresponding author. Department of Pharmacy, the Affiliated Brain Hospital of Guangzhou Medical University, 36 Mingxin Road, Guangzhou 510370, China.Department of Pharmacy, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China; Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China; Corresponding author. Department of Pharmacy, the Affiliated Brain Hospital of Guangzhou Medical University, 36 Mingxin Road, Guangzhou 510370, China.Alzheimer's disease (AD) has attracted considerable attention from the public and scientific researchers, leading to a rapid growth in relevant research on this disorder in the last 10 years. The present study aimed to conduct a bibliometric analysis to elucidate the trends of global research on the role of apolipoprotein E in AD in the past decade. Three bibliometric software (CiteSpace, VOSviewer, and R Bibliometrix) were used to analyze the active journals, countries/regions, institutes, authors, co-cited references, and keywords in this field. The USA was the most influential country, and the University of California was the most productive institute. Zetterberg H contributed the highest number of publications, and Petersen RC was the most cited author in this field. On the basis of the co-cited reference analysis, knowledge base on biomarkers, risk factors, and mechanisms were updated in the past decade. Current research hotspots are shifting to tau-related mechanisms and identification of genetic risk factors. Our study provides insights into the developing knowledge base and trends related to research on apolipoprotein E in AD, which may provide new directions for further research in this field.http://www.sciencedirect.com/science/article/pii/S2405844023051952Alzheimer's diseaseApolipoprotein EBiomarkerMechanismRisk factor |
| spellingShingle | Zhanzhang Wang Xiuqing Zhu Yuguan Wen Dewei Shang Bibliometric analysis of global research on the role of apolipoprotein E in Alzheimer's disease Heliyon Alzheimer's disease Apolipoprotein E Biomarker Mechanism Risk factor |
| title | Bibliometric analysis of global research on the role of apolipoprotein E in Alzheimer's disease |
| title_full | Bibliometric analysis of global research on the role of apolipoprotein E in Alzheimer's disease |
| title_fullStr | Bibliometric analysis of global research on the role of apolipoprotein E in Alzheimer's disease |
| title_full_unstemmed | Bibliometric analysis of global research on the role of apolipoprotein E in Alzheimer's disease |
| title_short | Bibliometric analysis of global research on the role of apolipoprotein E in Alzheimer's disease |
| title_sort | bibliometric analysis of global research on the role of apolipoprotein e in alzheimer s disease |
| topic | Alzheimer's disease Apolipoprotein E Biomarker Mechanism Risk factor |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023051952 |
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