High-Performance Liquid Chromatography-Tandem Mass Spectrometry for Buprenorphine Evaluation in Plasma—Application to Pharmacokinetic Studies in Rabbits

High-Performance Liquid Chromatography-Tandem Mass Spectrometry for Buprenorphine Evaluation in Plasma—Application to Pharmacokinetic Studies in Rabbits

The precise and reliable determination of buprenorphine concentration is fundamental in certain medical or research applications, particularly in pharmacokinetic studies of this opioid. The main challenge is, however, the development of an analytical method that is sensitive enough, as the detected...

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Bibliographic Details
Main Authors: Marta Tikhomirov, Błażej Poźniak, Tomasz Śniegocki
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
buprenorphine
mass spectrometry
pharmacokinetics
rabbit
Online Access:https://www.mdpi.com/1420-3049/26/2/437

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