Prediction of mechanical ventilation outcome by early abdominal-visceral-blood-flow-and-function score in critically ill patients after cardiopulmonary bypass in the ICU: A prospective observational study
Background: Abdominal organs are important organs that sense and respond to ischemia and hypoxia, but there are few evaluation methods.We use ultrasonography to evaluate abdominal organ function and blood flow in patients with mechanical ventilation (MV) after cardiopulmonary bypass and to obtain a...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | Journal of Intensive Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667100X23000622 |
| _version_ | 1797359875077963776 |
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| author | Chaofu Yue Longxiang Su Jun Wang Na Cui Yuankai Zhou Wei Cheng Bo Tang Xi Rui Huaiwu He Yun Long |
| author_facet | Chaofu Yue Longxiang Su Jun Wang Na Cui Yuankai Zhou Wei Cheng Bo Tang Xi Rui Huaiwu He Yun Long |
| author_sort | Chaofu Yue |
| collection | DOAJ |
| description | Background: Abdominal organs are important organs that sense and respond to ischemia and hypoxia, but there are few evaluation methods.We use ultrasonography to evaluate abdominal organ function and blood flow in patients with mechanical ventilation (MV) after cardiopulmonary bypass and to obtain a semiquantitative score for abdominal organ function and blood flow. Methods: Patients with cardiopulmonary bypass in the Critical Care Department of Peking Union Medical College Hospital in China from March to July 2021 were enrolled in this prospective observational study. The correlation of the abdominal-visceral-blood-flow-and-function score (AVBFS) with the duration of MV, number of days spent in the intensive care unit (ICU), acute physiology and chronic health evaluation II (APACHE-II), sequential organ failure assessment (SOFA), lactate, epinephrine, and norepinephrine use was analyzed, and the results were used to assess the predictive value of the receiver operating characteristic curve (ROC) regression analysis score for the duration of MV. Results: Of the 92 patients who underwent cardiopulmonary bypass, 41 were finally included. The AVBFS were significantly correlated with the duration of MV, number of days spent in the ICU, APACHE-II score, SOFA score, and norepinephrine use time. The AVBFS in a group of patients using ventilators ≥36 h were significantly higher than those obtained for a group of patients using ventilators <36 h (P <0.05). The evaluation results for the AVBFS at 0-12 h after ICU admission were as follows: area under the ROC curve (AUC)=0.876 (95% confidence interval [CI]: 0.767 to 0.984), cut-off value=2.5, specificity=0.842, and sensitivity=0.773. Conclusions: Abdominal visceral organ function and blood perfusion can be used to evaluate gastrointestinal function. It is related to early and late extubation after cardiac surgery. |
| first_indexed | 2024-03-08T15:31:17Z |
| format | Article |
| id | doaj.art-0e5543e67d93415aba23e3148038ed15 |
| institution | Directory Open Access Journal |
| issn | 2667-100X |
| language | English |
| last_indexed | 2024-03-08T15:31:17Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Intensive Medicine |
| spelling | doaj.art-0e5543e67d93415aba23e3148038ed152024-01-10T04:39:31ZengElsevierJournal of Intensive Medicine2667-100X2024-01-0141101107Prediction of mechanical ventilation outcome by early abdominal-visceral-blood-flow-and-function score in critically ill patients after cardiopulmonary bypass in the ICU: A prospective observational studyChaofu Yue0Longxiang Su1Jun Wang2Na Cui3Yuankai Zhou4Wei Cheng5Bo Tang6Xi Rui7Huaiwu He8Yun Long9Department of Intensive Care Unit, Peking Union Medical College Hospital, Beijing, China; Department of Intensive Care Unit, Qujing First People's Hospital, Qujing, Yunnan, ChinaDepartment of Intensive Care Unit, Peking Union Medical College Hospital, Beijing, ChinaDepartment of Intensive Care Unit, Peking Union Medical College Hospital, Beijing, China; Department of Intensive Care Unit, Shiyan People's Hospital of Bao'an District, Shenzhen, Guangdong, ChinaDepartment of Intensive Care Unit, Peking Union Medical College Hospital, Beijing, ChinaDepartment of Intensive Care Unit, Peking Union Medical College Hospital, Beijing, ChinaDepartment of Intensive Care Unit, Peking Union Medical College Hospital, Beijing, ChinaDepartment of Intensive Care Unit, Peking Union Medical College Hospital, Beijing, ChinaDepartment of Intensive Care Unit, Peking Union Medical College Hospital, Beijing, ChinaDepartment of Intensive Care Unit, Peking Union Medical College Hospital, Beijing, ChinaDepartment of Intensive Care Unit, Peking Union Medical College Hospital, Beijing, China; Corresponding author: Yun Long, Department of Intensive Care Unit, Peking Union Medical College Hospital, Beijing 100000, China.Background: Abdominal organs are important organs that sense and respond to ischemia and hypoxia, but there are few evaluation methods.We use ultrasonography to evaluate abdominal organ function and blood flow in patients with mechanical ventilation (MV) after cardiopulmonary bypass and to obtain a semiquantitative score for abdominal organ function and blood flow. Methods: Patients with cardiopulmonary bypass in the Critical Care Department of Peking Union Medical College Hospital in China from March to July 2021 were enrolled in this prospective observational study. The correlation of the abdominal-visceral-blood-flow-and-function score (AVBFS) with the duration of MV, number of days spent in the intensive care unit (ICU), acute physiology and chronic health evaluation II (APACHE-II), sequential organ failure assessment (SOFA), lactate, epinephrine, and norepinephrine use was analyzed, and the results were used to assess the predictive value of the receiver operating characteristic curve (ROC) regression analysis score for the duration of MV. Results: Of the 92 patients who underwent cardiopulmonary bypass, 41 were finally included. The AVBFS were significantly correlated with the duration of MV, number of days spent in the ICU, APACHE-II score, SOFA score, and norepinephrine use time. The AVBFS in a group of patients using ventilators ≥36 h were significantly higher than those obtained for a group of patients using ventilators <36 h (P <0.05). The evaluation results for the AVBFS at 0-12 h after ICU admission were as follows: area under the ROC curve (AUC)=0.876 (95% confidence interval [CI]: 0.767 to 0.984), cut-off value=2.5, specificity=0.842, and sensitivity=0.773. Conclusions: Abdominal visceral organ function and blood perfusion can be used to evaluate gastrointestinal function. It is related to early and late extubation after cardiac surgery.http://www.sciencedirect.com/science/article/pii/S2667100X23000622Ultrasonic evaluationAbdominal-visceral-blood-flow-and-function score (AVBFS)Gastrointestinal dysfunctionMechanical ventilationCardiopulmonary bypass |
| spellingShingle | Chaofu Yue Longxiang Su Jun Wang Na Cui Yuankai Zhou Wei Cheng Bo Tang Xi Rui Huaiwu He Yun Long Prediction of mechanical ventilation outcome by early abdominal-visceral-blood-flow-and-function score in critically ill patients after cardiopulmonary bypass in the ICU: A prospective observational study Journal of Intensive Medicine Ultrasonic evaluation Abdominal-visceral-blood-flow-and-function score (AVBFS) Gastrointestinal dysfunction Mechanical ventilation Cardiopulmonary bypass |
| title | Prediction of mechanical ventilation outcome by early abdominal-visceral-blood-flow-and-function score in critically ill patients after cardiopulmonary bypass in the ICU: A prospective observational study |
| title_full | Prediction of mechanical ventilation outcome by early abdominal-visceral-blood-flow-and-function score in critically ill patients after cardiopulmonary bypass in the ICU: A prospective observational study |
| title_fullStr | Prediction of mechanical ventilation outcome by early abdominal-visceral-blood-flow-and-function score in critically ill patients after cardiopulmonary bypass in the ICU: A prospective observational study |
| title_full_unstemmed | Prediction of mechanical ventilation outcome by early abdominal-visceral-blood-flow-and-function score in critically ill patients after cardiopulmonary bypass in the ICU: A prospective observational study |
| title_short | Prediction of mechanical ventilation outcome by early abdominal-visceral-blood-flow-and-function score in critically ill patients after cardiopulmonary bypass in the ICU: A prospective observational study |
| title_sort | prediction of mechanical ventilation outcome by early abdominal visceral blood flow and function score in critically ill patients after cardiopulmonary bypass in the icu a prospective observational study |
| topic | Ultrasonic evaluation Abdominal-visceral-blood-flow-and-function score (AVBFS) Gastrointestinal dysfunction Mechanical ventilation Cardiopulmonary bypass |
| url | http://www.sciencedirect.com/science/article/pii/S2667100X23000622 |
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