Genome-Wide Association Study Identifies Eight Novel Loci for Susceptibility of Scrub Typhus and Highlights Immune-Related Signaling Pathways in Its Pathogenesis

Genome-Wide Association Study Identifies Eight Novel Loci for Susceptibility of Scrub Typhus and Highlights Immune-Related Signaling Pathways in Its Pathogenesis

Scrub typhus is a fatal zoonotic disease caused by <i>Orientia tsutsugamushi</i>. This disease is accompanied by systemic vasculitis, lymphadenopathy, headache, myalgia, and eschar. In recent studies, a novel strain that is resistant to current medical treatment was identified in Thailan...

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Bibliographic Details
Main Authors: Yong-Chan Kim, Soriul Kim, Hee-Kwon Kim, Yi Lee, Chol Shin, Chang-Seop Lee, Byung-Hoon Jeong
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
scrub typhus
<i>Orientia tsutsugamushi</i>
genome-wide association study
GWAS
MIST
PANTHER
Online Access:https://www.mdpi.com/2073-4409/10/3/570

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