An autopsy study of the spectrum of severe COVID-19 in children: From SARS to different phenotypes of MIS-C

An autopsy study of the spectrum of severe COVID-19 in children: From SARS to different phenotypes of MIS-C

Background: COVID-19 in children is usually mild or asymptomatic, but severe and fatal paediatric cases have been described. The pathology of COVID-19 in children is not known; the proposed pathogenesis for severe cases includes immune-mediated mechanisms or the direct effect of SARS-CoV-2 on tissue...

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Main Authors: Amaro Nunes Duarte-Neto, Elia Garcia Caldini, Michele Soares Gomes-Gouvêa, Cristina Takami Kanamura, Renata Aparecida de Almeida Monteiro, Juliana Ferreira Ferranti, Andrea Maria Cordeiro Ventura, Fabiane Aliotti Regalio, Daniela Matos Fiorenzano, Maria Augusta Bento Cicaroni Gibelli, Werther Brunow de Carvalho, Gabriela Nunes Leal, João Renato Rebello Pinho, Artur Figueiredo Delgado, Magda Carneiro-Sampaio, Thais Mauad, Luiz Fernando Ferraz da Silva, Paulo Hilario Nascimento Saldiva, Marisa Dolhnikoff
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:EClinicalMedicine
Subjects:
Covid-19
Sars-cov-2
Autopsy
Pathology
Minimally invasive autopsy
Children
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537021001309

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