Cytomegalovirus ileocolitis in a rheumatoid arthritis patient: case report and literature review

Rheumatoid arthritis (RA) is an autoimmune, systemic, chronic, inflammatory disease generally treated with various immunosuppressive drugs. Cytomegalovirus (CMV) is an opportunistic, viral infection that is commonly seen in immunosuppressed patients. A sixty-four-year old female diagnosed with RA an...

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Main Authors: M. S. Dag, I. H. Turkbeyler, Z. A. Ozturk, B. Kısacık, E. Tutar, A. Kadayıfçı
Format: Article
Language:English
Published: PAGEPress Publications 2015-06-01
Series:Reumatismo
Subjects:
Online Access:http://www.reumatismo.org/index.php/reuma/article/view/793
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author M. S. Dag
I. H. Turkbeyler
Z. A. Ozturk
B. Kısacık
E. Tutar
A. Kadayıfçı
author_facet M. S. Dag
I. H. Turkbeyler
Z. A. Ozturk
B. Kısacık
E. Tutar
A. Kadayıfçı
author_sort M. S. Dag
collection DOAJ
description Rheumatoid arthritis (RA) is an autoimmune, systemic, chronic, inflammatory disease generally treated with various immunosuppressive drugs. Cytomegalovirus (CMV) is an opportunistic, viral infection that is commonly seen in immunosuppressed patients. A sixty-four-year old female diagnosed with RA and treated with immunosuppressive agents was admitted to our rheumatology outpatient service with complaints of diarrhea and abdominal pain, which had lasted longer than four weeks. The patient’s colonoscopy revealed inflamed and ulcerated areas in the colon and in the terminal ileum. A biopsy showed intra-nuclear inclusion particles consistent with CMV. We started an oral valganciclovir therapy in this serum-CMV-polymerase chain reactionpositive patient. The concomitant use of immunosuppressive agents and anti-viral drugs eased the patient’s complaints, and the endoscopic picture improved. Consequently, cytomegalovirus ileocolitis in immunosuppressed patients admitted with severe diarrhea must be considered in the differential diagnosis.
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spelling doaj.art-0e5c30a2f1cb4b7ab646ac40210ecd072022-12-22T02:10:26ZengPAGEPress PublicationsReumatismo0048-74492240-26832015-06-01671131610.4081/reumatismo.2015.793676Cytomegalovirus ileocolitis in a rheumatoid arthritis patient: case report and literature reviewM. S. Dag0I. H. Turkbeyler1Z. A. Ozturk2B. Kısacık3E. Tutar4A. Kadayıfçı5Department of Internal Medicine, School of Medicine, Gaziantep UniversityDepartment of Internal Medicine, School of Medicine, Gaziantep UniversityDepartment of Internal Medicine, School of Medicine, Gaziantep UniversityDepartment of Internal Medicine, School of Medicine, Gaziantep UniversityDepartment of Internal Medicine, School of Medicine, Gaziantep UniversityDepartment of Internal Medicine, School of Medicine, Gaziantep UniversityRheumatoid arthritis (RA) is an autoimmune, systemic, chronic, inflammatory disease generally treated with various immunosuppressive drugs. Cytomegalovirus (CMV) is an opportunistic, viral infection that is commonly seen in immunosuppressed patients. A sixty-four-year old female diagnosed with RA and treated with immunosuppressive agents was admitted to our rheumatology outpatient service with complaints of diarrhea and abdominal pain, which had lasted longer than four weeks. The patient’s colonoscopy revealed inflamed and ulcerated areas in the colon and in the terminal ileum. A biopsy showed intra-nuclear inclusion particles consistent with CMV. We started an oral valganciclovir therapy in this serum-CMV-polymerase chain reactionpositive patient. The concomitant use of immunosuppressive agents and anti-viral drugs eased the patient’s complaints, and the endoscopic picture improved. Consequently, cytomegalovirus ileocolitis in immunosuppressed patients admitted with severe diarrhea must be considered in the differential diagnosis.http://www.reumatismo.org/index.php/reuma/article/view/793Rheumatoid arthritis, Cytomegalovirus, Ileocolitis.
spellingShingle M. S. Dag
I. H. Turkbeyler
Z. A. Ozturk
B. Kısacık
E. Tutar
A. Kadayıfçı
Cytomegalovirus ileocolitis in a rheumatoid arthritis patient: case report and literature review
Reumatismo
Rheumatoid arthritis, Cytomegalovirus, Ileocolitis.
title Cytomegalovirus ileocolitis in a rheumatoid arthritis patient: case report and literature review
title_full Cytomegalovirus ileocolitis in a rheumatoid arthritis patient: case report and literature review
title_fullStr Cytomegalovirus ileocolitis in a rheumatoid arthritis patient: case report and literature review
title_full_unstemmed Cytomegalovirus ileocolitis in a rheumatoid arthritis patient: case report and literature review
title_short Cytomegalovirus ileocolitis in a rheumatoid arthritis patient: case report and literature review
title_sort cytomegalovirus ileocolitis in a rheumatoid arthritis patient case report and literature review
topic Rheumatoid arthritis, Cytomegalovirus, Ileocolitis.
url http://www.reumatismo.org/index.php/reuma/article/view/793
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