Cytomegalovirus ileocolitis in a rheumatoid arthritis patient: case report and literature review
Rheumatoid arthritis (RA) is an autoimmune, systemic, chronic, inflammatory disease generally treated with various immunosuppressive drugs. Cytomegalovirus (CMV) is an opportunistic, viral infection that is commonly seen in immunosuppressed patients. A sixty-four-year old female diagnosed with RA an...
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Format: | Article |
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PAGEPress Publications
2015-06-01
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Series: | Reumatismo |
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Online Access: | http://www.reumatismo.org/index.php/reuma/article/view/793 |
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author | M. S. Dag I. H. Turkbeyler Z. A. Ozturk B. Kısacık E. Tutar A. Kadayıfçı |
author_facet | M. S. Dag I. H. Turkbeyler Z. A. Ozturk B. Kısacık E. Tutar A. Kadayıfçı |
author_sort | M. S. Dag |
collection | DOAJ |
description | Rheumatoid arthritis (RA) is an autoimmune, systemic, chronic, inflammatory disease generally treated with various immunosuppressive drugs. Cytomegalovirus (CMV) is an opportunistic, viral infection that is commonly seen in immunosuppressed patients. A sixty-four-year old female diagnosed with RA and treated with immunosuppressive agents was admitted to our rheumatology outpatient service with complaints of diarrhea and abdominal pain, which had lasted longer than four weeks. The patient’s colonoscopy revealed inflamed and ulcerated areas in the colon and in the terminal ileum. A biopsy showed intra-nuclear inclusion particles consistent with CMV. We started an oral valganciclovir therapy in this serum-CMV-polymerase chain reactionpositive patient. The concomitant use of immunosuppressive agents and anti-viral drugs eased the patient’s complaints, and the endoscopic picture improved. Consequently, cytomegalovirus ileocolitis in immunosuppressed patients admitted with severe diarrhea must be considered in the differential diagnosis. |
first_indexed | 2024-04-14T05:14:12Z |
format | Article |
id | doaj.art-0e5c30a2f1cb4b7ab646ac40210ecd07 |
institution | Directory Open Access Journal |
issn | 0048-7449 2240-2683 |
language | English |
last_indexed | 2024-04-14T05:14:12Z |
publishDate | 2015-06-01 |
publisher | PAGEPress Publications |
record_format | Article |
series | Reumatismo |
spelling | doaj.art-0e5c30a2f1cb4b7ab646ac40210ecd072022-12-22T02:10:26ZengPAGEPress PublicationsReumatismo0048-74492240-26832015-06-01671131610.4081/reumatismo.2015.793676Cytomegalovirus ileocolitis in a rheumatoid arthritis patient: case report and literature reviewM. S. Dag0I. H. Turkbeyler1Z. A. Ozturk2B. Kısacık3E. Tutar4A. Kadayıfçı5Department of Internal Medicine, School of Medicine, Gaziantep UniversityDepartment of Internal Medicine, School of Medicine, Gaziantep UniversityDepartment of Internal Medicine, School of Medicine, Gaziantep UniversityDepartment of Internal Medicine, School of Medicine, Gaziantep UniversityDepartment of Internal Medicine, School of Medicine, Gaziantep UniversityDepartment of Internal Medicine, School of Medicine, Gaziantep UniversityRheumatoid arthritis (RA) is an autoimmune, systemic, chronic, inflammatory disease generally treated with various immunosuppressive drugs. Cytomegalovirus (CMV) is an opportunistic, viral infection that is commonly seen in immunosuppressed patients. A sixty-four-year old female diagnosed with RA and treated with immunosuppressive agents was admitted to our rheumatology outpatient service with complaints of diarrhea and abdominal pain, which had lasted longer than four weeks. The patient’s colonoscopy revealed inflamed and ulcerated areas in the colon and in the terminal ileum. A biopsy showed intra-nuclear inclusion particles consistent with CMV. We started an oral valganciclovir therapy in this serum-CMV-polymerase chain reactionpositive patient. The concomitant use of immunosuppressive agents and anti-viral drugs eased the patient’s complaints, and the endoscopic picture improved. Consequently, cytomegalovirus ileocolitis in immunosuppressed patients admitted with severe diarrhea must be considered in the differential diagnosis.http://www.reumatismo.org/index.php/reuma/article/view/793Rheumatoid arthritis, Cytomegalovirus, Ileocolitis. |
spellingShingle | M. S. Dag I. H. Turkbeyler Z. A. Ozturk B. Kısacık E. Tutar A. Kadayıfçı Cytomegalovirus ileocolitis in a rheumatoid arthritis patient: case report and literature review Reumatismo Rheumatoid arthritis, Cytomegalovirus, Ileocolitis. |
title | Cytomegalovirus ileocolitis in a rheumatoid arthritis patient: case report and literature review |
title_full | Cytomegalovirus ileocolitis in a rheumatoid arthritis patient: case report and literature review |
title_fullStr | Cytomegalovirus ileocolitis in a rheumatoid arthritis patient: case report and literature review |
title_full_unstemmed | Cytomegalovirus ileocolitis in a rheumatoid arthritis patient: case report and literature review |
title_short | Cytomegalovirus ileocolitis in a rheumatoid arthritis patient: case report and literature review |
title_sort | cytomegalovirus ileocolitis in a rheumatoid arthritis patient case report and literature review |
topic | Rheumatoid arthritis, Cytomegalovirus, Ileocolitis. |
url | http://www.reumatismo.org/index.php/reuma/article/view/793 |
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