Biosynthesis and antibacterial activity of MgO-NPs produced from Camellia-sinensis leaves extract
Magnesium oxides nanoparticles (MgO-NPs) were synthesized by a novel technique based on the leaf extract of Camellia sinensis (Green tea). The synthesized nanoparticles were evaluated for antibacterial activity (against both gram-positive and gram-negative pathogens) and therefore can be a suitable...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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IOP Publishing
2020-01-01
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| Series: | Materials Research Express |
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| Online Access: | https://doi.org/10.1088/2053-1591/abd421 |
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| author | Abdulhameed Khan Dania Shabir Pervaiz Ahmad Mayeen Uddin Khandaker M R I Faruque Israf Ud Din |
| author_facet | Abdulhameed Khan Dania Shabir Pervaiz Ahmad Mayeen Uddin Khandaker M R I Faruque Israf Ud Din |
| author_sort | Abdulhameed Khan |
| collection | DOAJ |
| description | Magnesium oxides nanoparticles (MgO-NPs) were synthesized by a novel technique based on the leaf extract of Camellia sinensis (Green tea). The synthesized nanoparticles were evaluated for antibacterial activity (against both gram-positive and gram-negative pathogens) and therefore can be a suitable therapeutic alternative to the usage of antibiotics. The antibacterial activity of synthesized MgO-NPs is tested against clinical isolates of gram-negative ( Escherichia coli, Pseudomonas aeruginosa, Serratia mercescens, Klebsiella pneumoniae ) and gram-positive ( Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes ) pathogenic bacteria. Agar well diffusion assay data indicate that MgO-NPs exhibit antibacterial activity at all concentrations tested against both gram-negative and gram-positive pathogenic bacteria, producing zone of inhibition (ZOI) in the range of 9.6 ± 1.1 to 21.0 ± 1.5 mm diameters. The maximum response is observed at 25 μ g ml ^−1 concentration of MgO-NPs, producing a zone of inhibition ranging from 15 ± 1.2 mm ( E.coli ) mm to 21.0 ± 1.5 mm ( S. marcescens) . |
| first_indexed | 2024-03-12T15:42:45Z |
| format | Article |
| id | doaj.art-0e5c9f06d61d4369a4efba333dc0e0c2 |
| institution | Directory Open Access Journal |
| issn | 2053-1591 |
| language | English |
| last_indexed | 2024-03-12T15:42:45Z |
| publishDate | 2020-01-01 |
| publisher | IOP Publishing |
| record_format | Article |
| series | Materials Research Express |
| spelling | doaj.art-0e5c9f06d61d4369a4efba333dc0e0c22023-08-09T15:53:56ZengIOP PublishingMaterials Research Express2053-15912020-01-018101540210.1088/2053-1591/abd421Biosynthesis and antibacterial activity of MgO-NPs produced from Camellia-sinensis leaves extractAbdulhameed Khan0Dania Shabir1Pervaiz Ahmad2Mayeen Uddin Khandaker3M R I Faruque4https://orcid.org/0000-0003-4086-7672Israf Ud Din5https://orcid.org/0000-0003-4021-7100Department of Biotechnology, University of Azad Jammu and Kashmir , 13100 Muzaffarabad, PakistanDepartment of Biotechnology, University of Azad Jammu and Kashmir , 13100 Muzaffarabad, PakistanDepartment of Physics, University of Azad Jammu and Kashmir , 13100 Muzaffarabad, PakistanCenter for Applied Physics and Radiation Technology, School of Engineering and Technology, Sunway University , 47500 Bandar Sunway, Selangor, MalaysiaSpace Science Centre, Universiti Kebangsaan Malaysia , 43600 UKM, Bangi, Selangor, MalaysiaDepartment of Chemistry, College of Science and Humanities, Prince Sattam bin Abdulaziz University , PO Box 173, Al-Kharj, 11942, Saudi ArabiaMagnesium oxides nanoparticles (MgO-NPs) were synthesized by a novel technique based on the leaf extract of Camellia sinensis (Green tea). The synthesized nanoparticles were evaluated for antibacterial activity (against both gram-positive and gram-negative pathogens) and therefore can be a suitable therapeutic alternative to the usage of antibiotics. The antibacterial activity of synthesized MgO-NPs is tested against clinical isolates of gram-negative ( Escherichia coli, Pseudomonas aeruginosa, Serratia mercescens, Klebsiella pneumoniae ) and gram-positive ( Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes ) pathogenic bacteria. Agar well diffusion assay data indicate that MgO-NPs exhibit antibacterial activity at all concentrations tested against both gram-negative and gram-positive pathogenic bacteria, producing zone of inhibition (ZOI) in the range of 9.6 ± 1.1 to 21.0 ± 1.5 mm diameters. The maximum response is observed at 25 μ g ml ^−1 concentration of MgO-NPs, producing a zone of inhibition ranging from 15 ± 1.2 mm ( E.coli ) mm to 21.0 ± 1.5 mm ( S. marcescens) .https://doi.org/10.1088/2053-1591/abd421Magnesium-OxideGreen-SynthesisCamellia-sinensisantibacterial-activity |
| spellingShingle | Abdulhameed Khan Dania Shabir Pervaiz Ahmad Mayeen Uddin Khandaker M R I Faruque Israf Ud Din Biosynthesis and antibacterial activity of MgO-NPs produced from Camellia-sinensis leaves extract Materials Research Express Magnesium-Oxide Green-Synthesis Camellia-sinensis antibacterial-activity |
| title | Biosynthesis and antibacterial activity of MgO-NPs produced from Camellia-sinensis leaves extract |
| title_full | Biosynthesis and antibacterial activity of MgO-NPs produced from Camellia-sinensis leaves extract |
| title_fullStr | Biosynthesis and antibacterial activity of MgO-NPs produced from Camellia-sinensis leaves extract |
| title_full_unstemmed | Biosynthesis and antibacterial activity of MgO-NPs produced from Camellia-sinensis leaves extract |
| title_short | Biosynthesis and antibacterial activity of MgO-NPs produced from Camellia-sinensis leaves extract |
| title_sort | biosynthesis and antibacterial activity of mgo nps produced from camellia sinensis leaves extract |
| topic | Magnesium-Oxide Green-Synthesis Camellia-sinensis antibacterial-activity |
| url | https://doi.org/10.1088/2053-1591/abd421 |
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