Inhibition of O-GlcNAc Transferase Alters the Differentiation and Maturation Process of Human Monocyte Derived Dendritic Cells

Inhibition of O-GlcNAc Transferase Alters the Differentiation and Maturation Process of Human Monocyte Derived Dendritic Cells

The O-GlcNAcylation is a posttranslational modification of proteins regulated by O-GlcNAc transferase (OGT) and O-GlcNAcase. These enzymes regulate the development, proliferation and function of cells, including the immune cells. Herein, we focused on the role of O-GlcNAcylation in human monocyte de...

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Bibliographic Details
Main Authors: Matjaž Weiss, Marko Anderluh, Martina Gobec
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
O-GlcNAcylation
O-GlcNAc transferase (OGT)
monocyte derived DCs
OSMI-1
immunometabolism
Online Access:https://www.mdpi.com/2073-4409/10/12/3312

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