High Prevalence of Hypovitaminosis D in Adolescents Attending a Reference Centre for the Treatment of Obesity in Switzerland
Background: Hypovitaminosis D is common in populations with obesity. This study aimed at assessing (1) the prevalence of hypovitaminosis D and (2) the associations between vitamin D levels and cardiovascular risk factors in adolescents attending a reference centre for the treatment of obesity. Desig...
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MDPI AG
2022-10-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/9/10/1527 |
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| author | Pollyanna Patriota Sylvie Borloz Inge Ruiz Thérèse Bouthors Serge Rezzi Pedro Marques-Vidal Michael Hauschild |
| author_facet | Pollyanna Patriota Sylvie Borloz Inge Ruiz Thérèse Bouthors Serge Rezzi Pedro Marques-Vidal Michael Hauschild |
| author_sort | Pollyanna Patriota |
| collection | DOAJ |
| description | Background: Hypovitaminosis D is common in populations with obesity. This study aimed at assessing (1) the prevalence of hypovitaminosis D and (2) the associations between vitamin D levels and cardiovascular risk factors in adolescents attending a reference centre for the treatment of obesity. Design: Cross-sectional pilot study conducted in the paediatric obesity unit of the Lausanne university hospital, Switzerland. Methods: Participants were considered eligible if they (1) were aged between 10 to 16.9 years and (2) consulted between 2017 and 2021. Participants were excluded if (1) they lacked vitamin D measurements or (2) the vitamin D measurement was performed one month after the base anthropometric assessment. Hypovitaminosis D was considered if the vitamin D level was <30 ng/mL (<75 nmol/L). Severe obesity was defined as a BMI z-score > 3 SD. Results: We included 52 adolescents (31% girls, mean age 13 ± 2 years, 33% with severe obesity). The prevalence of hypovitaminosis D was 87.5% in girls and 88.9% in boys. The vitamin D levels were inversely associated with BMI, Spearman r and 95% CI: −0.286 (−0.555; −0.017), <i>p</i> = 0.037; they were not associated with the BMI z-score: −0.052 (−0.327; 0.224), <i>p</i> = 0.713. The vitamin D levels were negatively associated with the parathormone levels (−0.353 (−0.667; −0.039), <i>p</i> = 0.028) and positively associated with the calcium levels (0.385 (0.061; 0.708), <i>p</i> = 0.020), while no association was found between vitamin D levels and blood pressure and lipid or glucose levels. Conclusion: almost 9 out of 10 adolescents with obesity in our cohort presented with hypovitaminosis D. Hypovitaminosis D does not seem to be associated with a higher cardiovascular risk profile in this group. |
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| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-09T20:26:52Z |
| publishDate | 2022-10-01 |
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| spelling | doaj.art-0e6985ee31714f8f9f4b4e19f49e9d022023-11-23T23:32:25ZengMDPI AGChildren2227-90672022-10-01910152710.3390/children9101527High Prevalence of Hypovitaminosis D in Adolescents Attending a Reference Centre for the Treatment of Obesity in SwitzerlandPollyanna Patriota0Sylvie Borloz1Inge Ruiz2Thérèse Bouthors3Serge Rezzi4Pedro Marques-Vidal5Michael Hauschild6Swiss Nutrition and Health Foundation, 1066 Epalinges, SwitzerlandPaediatric Endocrinology and Diabetology Unit, Service of Pediatrics, Department Women-Mother-Child—CHUV, Children’s Hospital—CHUV, Chem. de Montétan 16, 1004 Lausanne, SwitzerlandPaediatric Endocrinology and Diabetology Unit, Service of Pediatrics, Department Women-Mother-Child—CHUV, Children’s Hospital—CHUV, Chem. de Montétan 16, 1004 Lausanne, SwitzerlandPaediatric Endocrinology and Diabetology Unit, Service of Pediatrics, Department Women-Mother-Child—CHUV, Children’s Hospital—CHUV, Chem. de Montétan 16, 1004 Lausanne, SwitzerlandSwiss Nutrition and Health Foundation, 1066 Epalinges, SwitzerlandDepartment of Medicine, Internal Medicine, Lausanne University Hospital and University of Lausanne, 1015 Lausanne, SwitzerlandPaediatric Endocrinology and Diabetology Unit, Service of Pediatrics, Department Women-Mother-Child—CHUV, Children’s Hospital—CHUV, Chem. de Montétan 16, 1004 Lausanne, SwitzerlandBackground: Hypovitaminosis D is common in populations with obesity. This study aimed at assessing (1) the prevalence of hypovitaminosis D and (2) the associations between vitamin D levels and cardiovascular risk factors in adolescents attending a reference centre for the treatment of obesity. Design: Cross-sectional pilot study conducted in the paediatric obesity unit of the Lausanne university hospital, Switzerland. Methods: Participants were considered eligible if they (1) were aged between 10 to 16.9 years and (2) consulted between 2017 and 2021. Participants were excluded if (1) they lacked vitamin D measurements or (2) the vitamin D measurement was performed one month after the base anthropometric assessment. Hypovitaminosis D was considered if the vitamin D level was <30 ng/mL (<75 nmol/L). Severe obesity was defined as a BMI z-score > 3 SD. Results: We included 52 adolescents (31% girls, mean age 13 ± 2 years, 33% with severe obesity). The prevalence of hypovitaminosis D was 87.5% in girls and 88.9% in boys. The vitamin D levels were inversely associated with BMI, Spearman r and 95% CI: −0.286 (−0.555; −0.017), <i>p</i> = 0.037; they were not associated with the BMI z-score: −0.052 (−0.327; 0.224), <i>p</i> = 0.713. The vitamin D levels were negatively associated with the parathormone levels (−0.353 (−0.667; −0.039), <i>p</i> = 0.028) and positively associated with the calcium levels (0.385 (0.061; 0.708), <i>p</i> = 0.020), while no association was found between vitamin D levels and blood pressure and lipid or glucose levels. Conclusion: almost 9 out of 10 adolescents with obesity in our cohort presented with hypovitaminosis D. Hypovitaminosis D does not seem to be associated with a higher cardiovascular risk profile in this group.https://www.mdpi.com/2227-9067/9/10/1527adolescentsobesityhypovitaminosis DSwitzerland |
| spellingShingle | Pollyanna Patriota Sylvie Borloz Inge Ruiz Thérèse Bouthors Serge Rezzi Pedro Marques-Vidal Michael Hauschild High Prevalence of Hypovitaminosis D in Adolescents Attending a Reference Centre for the Treatment of Obesity in Switzerland Children adolescents obesity hypovitaminosis D Switzerland |
| title | High Prevalence of Hypovitaminosis D in Adolescents Attending a Reference Centre for the Treatment of Obesity in Switzerland |
| title_full | High Prevalence of Hypovitaminosis D in Adolescents Attending a Reference Centre for the Treatment of Obesity in Switzerland |
| title_fullStr | High Prevalence of Hypovitaminosis D in Adolescents Attending a Reference Centre for the Treatment of Obesity in Switzerland |
| title_full_unstemmed | High Prevalence of Hypovitaminosis D in Adolescents Attending a Reference Centre for the Treatment of Obesity in Switzerland |
| title_short | High Prevalence of Hypovitaminosis D in Adolescents Attending a Reference Centre for the Treatment of Obesity in Switzerland |
| title_sort | high prevalence of hypovitaminosis d in adolescents attending a reference centre for the treatment of obesity in switzerland |
| topic | adolescents obesity hypovitaminosis D Switzerland |
| url | https://www.mdpi.com/2227-9067/9/10/1527 |
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