Phenolic Compounds from <i>Sonchus arvensis</i> Linn. and <i>Hemerocallis citrina</i> Baroni. Inhibit Sucrose and Stearic Acid Induced Damage in <i>Caenorhabditis elegans</i>
<i>Sonchus arvensis</i> Linn. and <i>Hemerocallis citrina</i> Baroni. have been reported to improve body resistance. However, the underlying mechanism is not clear. In this study, <i>Sonchus arvensis</i> Linn. phenolic compounds (SAP) and <i>Hemerocallis cit...
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MDPI AG
2023-02-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/28/4/1707 |
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| author | Qin An Lei Zhang Xiyue Qin Xiong Wang Wenli Wang Qingyong Meng Yali Zhang |
| author_facet | Qin An Lei Zhang Xiyue Qin Xiong Wang Wenli Wang Qingyong Meng Yali Zhang |
| author_sort | Qin An |
| collection | DOAJ |
| description | <i>Sonchus arvensis</i> Linn. and <i>Hemerocallis citrina</i> Baroni. have been reported to improve body resistance. However, the underlying mechanism is not clear. In this study, <i>Sonchus arvensis</i> Linn. phenolic compounds (SAP) and <i>Hemerocallis citrina</i> Baroni. phenolic compounds (HCP) were extracted and their protective effects in <i>Caenorhabditis elegans</i> evaluated. SAP and HCP showed considerably different phenolic compositions. In the normal <i>C. elegans</i> model, HCP exhibited better effects in promoting growth than SAP. In the sucrose-incubated <i>C. elegans</i> model, both SAP and HCP showed positive effects against the high-sucrose-induced damage. In the stearic acid-incubated <i>C. elegans</i> model, both SAP and HCP improved lifespan, reproductive ability and growth, while HCP had a more evident effect than SAP on reproductive ability. The TGF-β signaling pathway was confirmed to be involved in the protective effects of SAP and HCP. The antioxidant ability of SAP was also found to be related to <i>skn-1</i>. Our study shows that both SAP and HCP have protective effects against high sucrose- or high stearic acid-induced damage. |
| first_indexed | 2024-03-11T08:21:45Z |
| format | Article |
| id | doaj.art-0e69d7e5cb934212bd7d3bfa07105f96 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-11T08:21:45Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-0e69d7e5cb934212bd7d3bfa07105f962023-11-16T22:22:09ZengMDPI AGMolecules1420-30492023-02-01284170710.3390/molecules28041707Phenolic Compounds from <i>Sonchus arvensis</i> Linn. and <i>Hemerocallis citrina</i> Baroni. Inhibit Sucrose and Stearic Acid Induced Damage in <i>Caenorhabditis elegans</i>Qin An0Lei Zhang1Xiyue Qin2Xiong Wang3Wenli Wang4Qingyong Meng5Yali Zhang6College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, ChinaCollege of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, ChinaCollege of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, ChinaCollege of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, ChinaCollege of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, ChinaCollege of Biological Sciences, China Agricultural University, Beijing 100193, ChinaCollege of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China<i>Sonchus arvensis</i> Linn. and <i>Hemerocallis citrina</i> Baroni. have been reported to improve body resistance. However, the underlying mechanism is not clear. In this study, <i>Sonchus arvensis</i> Linn. phenolic compounds (SAP) and <i>Hemerocallis citrina</i> Baroni. phenolic compounds (HCP) were extracted and their protective effects in <i>Caenorhabditis elegans</i> evaluated. SAP and HCP showed considerably different phenolic compositions. In the normal <i>C. elegans</i> model, HCP exhibited better effects in promoting growth than SAP. In the sucrose-incubated <i>C. elegans</i> model, both SAP and HCP showed positive effects against the high-sucrose-induced damage. In the stearic acid-incubated <i>C. elegans</i> model, both SAP and HCP improved lifespan, reproductive ability and growth, while HCP had a more evident effect than SAP on reproductive ability. The TGF-β signaling pathway was confirmed to be involved in the protective effects of SAP and HCP. The antioxidant ability of SAP was also found to be related to <i>skn-1</i>. Our study shows that both SAP and HCP have protective effects against high sucrose- or high stearic acid-induced damage.https://www.mdpi.com/1420-3049/28/4/1707Sonchus arvensis Linn.Hemerocallis citrina Baroni.phenolic compoundsCaenorhabditis elegansantioxidant |
| spellingShingle | Qin An Lei Zhang Xiyue Qin Xiong Wang Wenli Wang Qingyong Meng Yali Zhang Phenolic Compounds from <i>Sonchus arvensis</i> Linn. and <i>Hemerocallis citrina</i> Baroni. Inhibit Sucrose and Stearic Acid Induced Damage in <i>Caenorhabditis elegans</i> Molecules Sonchus arvensis Linn. Hemerocallis citrina Baroni. phenolic compounds Caenorhabditis elegans antioxidant |
| title | Phenolic Compounds from <i>Sonchus arvensis</i> Linn. and <i>Hemerocallis citrina</i> Baroni. Inhibit Sucrose and Stearic Acid Induced Damage in <i>Caenorhabditis elegans</i> |
| title_full | Phenolic Compounds from <i>Sonchus arvensis</i> Linn. and <i>Hemerocallis citrina</i> Baroni. Inhibit Sucrose and Stearic Acid Induced Damage in <i>Caenorhabditis elegans</i> |
| title_fullStr | Phenolic Compounds from <i>Sonchus arvensis</i> Linn. and <i>Hemerocallis citrina</i> Baroni. Inhibit Sucrose and Stearic Acid Induced Damage in <i>Caenorhabditis elegans</i> |
| title_full_unstemmed | Phenolic Compounds from <i>Sonchus arvensis</i> Linn. and <i>Hemerocallis citrina</i> Baroni. Inhibit Sucrose and Stearic Acid Induced Damage in <i>Caenorhabditis elegans</i> |
| title_short | Phenolic Compounds from <i>Sonchus arvensis</i> Linn. and <i>Hemerocallis citrina</i> Baroni. Inhibit Sucrose and Stearic Acid Induced Damage in <i>Caenorhabditis elegans</i> |
| title_sort | phenolic compounds from i sonchus arvensis i linn and i hemerocallis citrina i baroni inhibit sucrose and stearic acid induced damage in i caenorhabditis elegans i |
| topic | Sonchus arvensis Linn. Hemerocallis citrina Baroni. phenolic compounds Caenorhabditis elegans antioxidant |
| url | https://www.mdpi.com/1420-3049/28/4/1707 |
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