Haematophagous arthropod saliva and host defense system: a tale of tear and blood
The saliva from blood-feeding arthropod vectors is enriched with molecules that display diverse functions that mediate a successful blood meal. They function not only as weapons against host's haemostatic, inflammatory and immune responses but also as important tools to pathogen establishment....
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Academia Brasileira de Ciências
2005-01-01
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| Series: | Anais da Academia Brasileira de Ciências |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652005000400008 |
| _version_ | 1828278050759901184 |
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| author | Andrade Bruno B. Teixeira Clarissa R. Barral Aldina Barral-Netto Manoel |
| author_facet | Andrade Bruno B. Teixeira Clarissa R. Barral Aldina Barral-Netto Manoel |
| author_sort | Andrade Bruno B. |
| collection | DOAJ |
| description | The saliva from blood-feeding arthropod vectors is enriched with molecules that display diverse functions that mediate a successful blood meal. They function not only as weapons against host's haemostatic, inflammatory and immune responses but also as important tools to pathogen establishment. Parasites, virus and bacteria taking advantage of vectors' armament have adapted to facilitate their entry in the host. Today, many salivary molecules have been identified and characterized as new targets to the development of future vaccines. Here we focus on current information on vector's saliva and the molecules responsible to modify host's hemostasis and immune response, also regarding their role in disease transmission. |
| first_indexed | 2024-04-13T07:25:29Z |
| format | Article |
| id | doaj.art-0e6d09e6dba14976a4405f7e3d2b8b8e |
| institution | Directory Open Access Journal |
| issn | 0001-3765 1678-2690 |
| language | English |
| last_indexed | 2024-04-13T07:25:29Z |
| publishDate | 2005-01-01 |
| publisher | Academia Brasileira de Ciências |
| record_format | Article |
| series | Anais da Academia Brasileira de Ciências |
| spelling | doaj.art-0e6d09e6dba14976a4405f7e3d2b8b8e2022-12-22T02:56:30ZengAcademia Brasileira de CiênciasAnais da Academia Brasileira de Ciências0001-37651678-26902005-01-01774665693Haematophagous arthropod saliva and host defense system: a tale of tear and bloodAndrade Bruno B.Teixeira Clarissa R.Barral AldinaBarral-Netto ManoelThe saliva from blood-feeding arthropod vectors is enriched with molecules that display diverse functions that mediate a successful blood meal. They function not only as weapons against host's haemostatic, inflammatory and immune responses but also as important tools to pathogen establishment. Parasites, virus and bacteria taking advantage of vectors' armament have adapted to facilitate their entry in the host. Today, many salivary molecules have been identified and characterized as new targets to the development of future vaccines. Here we focus on current information on vector's saliva and the molecules responsible to modify host's hemostasis and immune response, also regarding their role in disease transmission.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652005000400008salivabiteshemostasishostvectorinfection |
| spellingShingle | Andrade Bruno B. Teixeira Clarissa R. Barral Aldina Barral-Netto Manoel Haematophagous arthropod saliva and host defense system: a tale of tear and blood Anais da Academia Brasileira de Ciências saliva bites hemostasis host vector infection |
| title | Haematophagous arthropod saliva and host defense system: a tale of tear and blood |
| title_full | Haematophagous arthropod saliva and host defense system: a tale of tear and blood |
| title_fullStr | Haematophagous arthropod saliva and host defense system: a tale of tear and blood |
| title_full_unstemmed | Haematophagous arthropod saliva and host defense system: a tale of tear and blood |
| title_short | Haematophagous arthropod saliva and host defense system: a tale of tear and blood |
| title_sort | haematophagous arthropod saliva and host defense system a tale of tear and blood |
| topic | saliva bites hemostasis host vector infection |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652005000400008 |
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