Corneal higher order aberrations by Sirius topography and their relation to different refractive errors
Abstract Purpose To compare the root mean square (RMS) of anterior corneal higher-order aberrations (HOAs) in ametropic and emmetropic eyes. Methods This retrospective observational study was conducted at the Department of Ophthalmology, Tishreen University Hospital, Latakia, Syria. Study eyes were...
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| Format: | Article |
| Language: | English |
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BMC
2023-03-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-023-02841-4 |
| _version_ | 1797865236891435008 |
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| author | Abdelrahman Salman Obeda Kailani Marwan Ghabra Rana Omran Taym R. Darwish Rafea Shaaban Hussein Ibrahim Hala Alhaji Hussam Khalil |
| author_facet | Abdelrahman Salman Obeda Kailani Marwan Ghabra Rana Omran Taym R. Darwish Rafea Shaaban Hussein Ibrahim Hala Alhaji Hussam Khalil |
| author_sort | Abdelrahman Salman |
| collection | DOAJ |
| description | Abstract Purpose To compare the root mean square (RMS) of anterior corneal higher-order aberrations (HOAs) in ametropic and emmetropic eyes. Methods This retrospective observational study was conducted at the Department of Ophthalmology, Tishreen University Hospital, Latakia, Syria. Study eyes were divided into four groups based on refractive error: mild-to-moderate myopia, hypermetropia, myopic astigmatism, and emmetropic eyes as controls. The following anterior corneal HOAs were evaluated using the Scheimpflug-Placido Sirius (CSO, Italy) tomographer over 6 mm pupil: Root mean square (RMS) total corneal HOAs, RMS trefoil, RMS coma and RMS spherical aberrations. Results RMS values of total HOAs, trefoil and coma showed statistically significant differences in all four groups (P < 0.05, all). HOAs were noted to be lowest in the control group (0.18 ± 0.09, 011 ± 0.08 and 0.09 ± 0.08 μm, respectively) and highest in the myopic astigmatism group (0.31 ± 0.16, 0.15 ± 0.12, 0.17 ± 0.14 μm, respectively). RMS spherical aberration was lowest in the astigmatism group (0.00 ± 0.16 μm) with a statistically significant difference from that in the control group (0.05 ± 0.07 μm, P = 0.049). Conclusion The mean RMS values of total HOAs, trefoil and coma were highest in the astigmatism group and lowest in the control group. However, spherical aberration was minimal in the astigmatism group. A better understanding and targeted treatment of higher-order aberrations in ametropic human eyes, and in particular eyes with astigmatism, may enhance visual quality and performance in the treatment of refractive errors. Recognising atypical HOAs may also assist in the early detection of pathological conditions such as keratoconus. |
| first_indexed | 2024-04-09T23:04:49Z |
| format | Article |
| id | doaj.art-0e6d76f6b3794c54a0bd54fd536856b4 |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-04-09T23:04:49Z |
| publishDate | 2023-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-0e6d76f6b3794c54a0bd54fd536856b42023-03-22T10:44:32ZengBMCBMC Ophthalmology1471-24152023-03-012311910.1186/s12886-023-02841-4Corneal higher order aberrations by Sirius topography and their relation to different refractive errorsAbdelrahman Salman0Obeda Kailani1Marwan Ghabra2Rana Omran3Taym R. Darwish4Rafea Shaaban5Hussein Ibrahim6Hala Alhaji7Hussam Khalil8Department of Ophthalmology, Tishreen UniversityDepartment of Ophthalmology, King’s College Hospital NHS Foundation TrustDepartment of Ophthalmology, Whipps Cross University HospitalDepartment of Ophthalmology, Eye Surgical HospitalDepartment of Ophthalmology, Tishreen UniversityDepartment of Ophthalmology, Tartous UniversityEye Surgical Hospital, Health MinistryDepartment of Ophthalmology, Tishreen UniversityEye Surgical Hospital, Health MinistryAbstract Purpose To compare the root mean square (RMS) of anterior corneal higher-order aberrations (HOAs) in ametropic and emmetropic eyes. Methods This retrospective observational study was conducted at the Department of Ophthalmology, Tishreen University Hospital, Latakia, Syria. Study eyes were divided into four groups based on refractive error: mild-to-moderate myopia, hypermetropia, myopic astigmatism, and emmetropic eyes as controls. The following anterior corneal HOAs were evaluated using the Scheimpflug-Placido Sirius (CSO, Italy) tomographer over 6 mm pupil: Root mean square (RMS) total corneal HOAs, RMS trefoil, RMS coma and RMS spherical aberrations. Results RMS values of total HOAs, trefoil and coma showed statistically significant differences in all four groups (P < 0.05, all). HOAs were noted to be lowest in the control group (0.18 ± 0.09, 011 ± 0.08 and 0.09 ± 0.08 μm, respectively) and highest in the myopic astigmatism group (0.31 ± 0.16, 0.15 ± 0.12, 0.17 ± 0.14 μm, respectively). RMS spherical aberration was lowest in the astigmatism group (0.00 ± 0.16 μm) with a statistically significant difference from that in the control group (0.05 ± 0.07 μm, P = 0.049). Conclusion The mean RMS values of total HOAs, trefoil and coma were highest in the astigmatism group and lowest in the control group. However, spherical aberration was minimal in the astigmatism group. A better understanding and targeted treatment of higher-order aberrations in ametropic human eyes, and in particular eyes with astigmatism, may enhance visual quality and performance in the treatment of refractive errors. Recognising atypical HOAs may also assist in the early detection of pathological conditions such as keratoconus.https://doi.org/10.1186/s12886-023-02841-4Zernike coefficientsCorneal Higher order aberrationsRefractive errorsSiriusAstigmatism |
| spellingShingle | Abdelrahman Salman Obeda Kailani Marwan Ghabra Rana Omran Taym R. Darwish Rafea Shaaban Hussein Ibrahim Hala Alhaji Hussam Khalil Corneal higher order aberrations by Sirius topography and their relation to different refractive errors BMC Ophthalmology Zernike coefficients Corneal Higher order aberrations Refractive errors Sirius Astigmatism |
| title | Corneal higher order aberrations by Sirius topography and their relation to different refractive errors |
| title_full | Corneal higher order aberrations by Sirius topography and their relation to different refractive errors |
| title_fullStr | Corneal higher order aberrations by Sirius topography and their relation to different refractive errors |
| title_full_unstemmed | Corneal higher order aberrations by Sirius topography and their relation to different refractive errors |
| title_short | Corneal higher order aberrations by Sirius topography and their relation to different refractive errors |
| title_sort | corneal higher order aberrations by sirius topography and their relation to different refractive errors |
| topic | Zernike coefficients Corneal Higher order aberrations Refractive errors Sirius Astigmatism |
| url | https://doi.org/10.1186/s12886-023-02841-4 |
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