Dose Analysis of Gadolinium Neutron Capture Therapy (GdNCT) on Cancer Using SHIELD-HIT12A

This research aimed to determine the dose of radiation received in cancer therapy for each decay of Gadolinium atomic nuclei with isotope 157 (157Gd) in Gadolinium Neutron Capture Therapy using the SHIELD-HIT12A program. Knowing the amount of dose given to cancer tissue should aid in minimizing the...

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Main Authors: Bagus Novrianto Fasni, Yohannes Sardjono, Boni Pahlanop Lapanporo
Format: Article
Language:English
Published: Universiti Brunei Darussalam 2018-12-01
Series:ASEAN Journal on Science and Technology for Development
Subjects:
Online Access:http://ajstd.org/index.php/ajstd/article/view/543
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author Bagus Novrianto Fasni
Yohannes Sardjono
Boni Pahlanop Lapanporo
author_facet Bagus Novrianto Fasni
Yohannes Sardjono
Boni Pahlanop Lapanporo
author_sort Bagus Novrianto Fasni
collection DOAJ
description This research aimed to determine the dose of radiation received in cancer therapy for each decay of Gadolinium atomic nuclei with isotope 157 (157Gd) in Gadolinium Neutron Capture Therapy using the SHIELD-HIT12A program. Knowing the amount of dose given to cancer tissue should aid in minimizing the damage that could occur in the healthy tissue around the cancer tissue, effectively killing only the cancer cells. The simulation employed in this research used the SHIELD-HIT12A program by providing input on beam.dat, mat.dat, detect.dat, and geo.dat files. The output data from the program comprised the value of recoil energy lost (energy absorbed into the target materials) for each of the 157Gd atomic nuclei, which was then processed by the dose determination equation to determine the dose given by the 157Gd nucleus to soft tissue. Based on the results, the amount of the dose given by each atomic nucleus 157Gd to soft tissue was 5.44 × 1011 Gy/decay.
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spelling doaj.art-0e6d9623bc864031b1fd71e15983969a2024-02-02T18:37:41ZengUniversiti Brunei DarussalamASEAN Journal on Science and Technology for Development0217-54602224-90282018-12-0135320921210.29037/ajstd.543543Dose Analysis of Gadolinium Neutron Capture Therapy (GdNCT) on Cancer Using SHIELD-HIT12ABagus Novrianto Fasni0Yohannes Sardjono1Boni Pahlanop Lapanporo2Department of Physics, Mathematics and Science Faculty, Tanjungpura University, Pontianak 78124, IndonesiaCenter of Accelerator Science and Technology, National Nuclear Energy Agency, Yogyakarta 55281, IndonesiaDepartment of Physics, Mathematics and Science Faculty, Tanjungpura University, Pontianak 78124, IndonesiaThis research aimed to determine the dose of radiation received in cancer therapy for each decay of Gadolinium atomic nuclei with isotope 157 (157Gd) in Gadolinium Neutron Capture Therapy using the SHIELD-HIT12A program. Knowing the amount of dose given to cancer tissue should aid in minimizing the damage that could occur in the healthy tissue around the cancer tissue, effectively killing only the cancer cells. The simulation employed in this research used the SHIELD-HIT12A program by providing input on beam.dat, mat.dat, detect.dat, and geo.dat files. The output data from the program comprised the value of recoil energy lost (energy absorbed into the target materials) for each of the 157Gd atomic nuclei, which was then processed by the dose determination equation to determine the dose given by the 157Gd nucleus to soft tissue. Based on the results, the amount of the dose given by each atomic nucleus 157Gd to soft tissue was 5.44 × 1011 Gy/decay.http://ajstd.org/index.php/ajstd/article/view/543157GdCancerGdNCTSHIELD-HIT12A
spellingShingle Bagus Novrianto Fasni
Yohannes Sardjono
Boni Pahlanop Lapanporo
Dose Analysis of Gadolinium Neutron Capture Therapy (GdNCT) on Cancer Using SHIELD-HIT12A
ASEAN Journal on Science and Technology for Development
157Gd
Cancer
GdNCT
SHIELD-HIT12A
title Dose Analysis of Gadolinium Neutron Capture Therapy (GdNCT) on Cancer Using SHIELD-HIT12A
title_full Dose Analysis of Gadolinium Neutron Capture Therapy (GdNCT) on Cancer Using SHIELD-HIT12A
title_fullStr Dose Analysis of Gadolinium Neutron Capture Therapy (GdNCT) on Cancer Using SHIELD-HIT12A
title_full_unstemmed Dose Analysis of Gadolinium Neutron Capture Therapy (GdNCT) on Cancer Using SHIELD-HIT12A
title_short Dose Analysis of Gadolinium Neutron Capture Therapy (GdNCT) on Cancer Using SHIELD-HIT12A
title_sort dose analysis of gadolinium neutron capture therapy gdnct on cancer using shield hit12a
topic 157Gd
Cancer
GdNCT
SHIELD-HIT12A
url http://ajstd.org/index.php/ajstd/article/view/543
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AT yohannessardjono doseanalysisofgadoliniumneutroncapturetherapygdnctoncancerusingshieldhit12a
AT bonipahlanoplapanporo doseanalysisofgadoliniumneutroncapturetherapygdnctoncancerusingshieldhit12a