Effect of Hydroalchoholic Extract 0f Trachyspermum Copticum on Anxiety in Male Rats
Anxiety is a common disorder of unknown origin is associated with an unpleasant feeling .According to the anxiolytic effects TC traditional medicine , trachyspermum Copticum effect on anxity male Wistar rats were investigated. trachyspermum copticum seed after detection by the University Herbarium,...
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| Format: | Article |
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Qom Islamic Azad University
2019-05-01
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| Series: | بیولوژی کاربردی |
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| Online Access: | https://sjoapb.qom.iau.ir/article_665016_b4721fb53fb41f86aa89799ea914b2f4.pdf |
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| author | زهره محمدی منش نسرین حیدریه |
| author_facet | زهره محمدی منش نسرین حیدریه |
| author_sort | زهره محمدی منش |
| collection | DOAJ |
| description | Anxiety is a common disorder of unknown origin is associated with an unpleasant feeling .According to the anxiolytic effects TC traditional medicine , trachyspermum Copticum effect on anxity male Wistar rats were investigated. trachyspermum copticum seed after detection by the University Herbarium, hydro-alcoholic extract was extracted by Soxhlet and the extract powder was prepared using smart legitimate. In this study, male Wistar rats (230 ± 20 g) were placed In groups intact, recipient of the DMSO (solvent extraction) (0.3 cc), received extract in different doses of 50, 25, 15 mg/kg. All injections were performed intraperitoneally. Half an hour after injection,anxity was measured using the elevated plus maze.Indicators of anxity for 5 minutes,including time spent and number of entries into the open arm was recorded. Data were analyzed by ANOVA statistical tests and Tukey test (p <0.05) .The results showed that the group receiving the extract solvent (DMSO) compared to intact in time spent and number of entries into the open arm does not show a significant difference. The group receiving a dose 15 mg/kg compared to the group receiving DMSO in time spent and number of entries into the open arm showed a significant increase. C. copticum hydro-alcoholic extract anxiolytic effects in low doses. Keywords: hydroalcoholic extract, Trachyspermum copticum, Anxiety, elevated plus maze, Male rats. |
| first_indexed | 2024-03-12T23:14:08Z |
| format | Article |
| id | doaj.art-0e6e99ef97b241bc80f32643d7d55cc2 |
| institution | Directory Open Access Journal |
| issn | 2538-3434 |
| language | fas |
| last_indexed | 2024-03-12T23:14:08Z |
| publishDate | 2019-05-01 |
| publisher | Qom Islamic Azad University |
| record_format | Article |
| series | بیولوژی کاربردی |
| spelling | doaj.art-0e6e99ef97b241bc80f32643d7d55cc22023-07-17T14:57:21ZfasQom Islamic Azad Universityبیولوژی کاربردی2538-34342019-05-0193319665016Effect of Hydroalchoholic Extract 0f Trachyspermum Copticum on Anxiety in Male Ratsزهره محمدی منش0نسرین حیدریه1گروه زیستشناسی، دانشگاه آزاد اسلامی، واحد قم، قم، ایرانعضو هیئت علمیAnxiety is a common disorder of unknown origin is associated with an unpleasant feeling .According to the anxiolytic effects TC traditional medicine , trachyspermum Copticum effect on anxity male Wistar rats were investigated. trachyspermum copticum seed after detection by the University Herbarium, hydro-alcoholic extract was extracted by Soxhlet and the extract powder was prepared using smart legitimate. In this study, male Wistar rats (230 ± 20 g) were placed In groups intact, recipient of the DMSO (solvent extraction) (0.3 cc), received extract in different doses of 50, 25, 15 mg/kg. All injections were performed intraperitoneally. Half an hour after injection,anxity was measured using the elevated plus maze.Indicators of anxity for 5 minutes,including time spent and number of entries into the open arm was recorded. Data were analyzed by ANOVA statistical tests and Tukey test (p <0.05) .The results showed that the group receiving the extract solvent (DMSO) compared to intact in time spent and number of entries into the open arm does not show a significant difference. The group receiving a dose 15 mg/kg compared to the group receiving DMSO in time spent and number of entries into the open arm showed a significant increase. C. copticum hydro-alcoholic extract anxiolytic effects in low doses. Keywords: hydroalcoholic extract, Trachyspermum copticum, Anxiety, elevated plus maze, Male rats.https://sjoapb.qom.iau.ir/article_665016_b4721fb53fb41f86aa89799ea914b2f4.pdfhydroalcoholic extracttrachyspermum copticumanxietyelevated plus mazemale rats |
| spellingShingle | زهره محمدی منش نسرین حیدریه Effect of Hydroalchoholic Extract 0f Trachyspermum Copticum on Anxiety in Male Rats بیولوژی کاربردی hydroalcoholic extract trachyspermum copticum anxiety elevated plus maze male rats |
| title | Effect of Hydroalchoholic Extract 0f Trachyspermum Copticum on Anxiety in Male Rats |
| title_full | Effect of Hydroalchoholic Extract 0f Trachyspermum Copticum on Anxiety in Male Rats |
| title_fullStr | Effect of Hydroalchoholic Extract 0f Trachyspermum Copticum on Anxiety in Male Rats |
| title_full_unstemmed | Effect of Hydroalchoholic Extract 0f Trachyspermum Copticum on Anxiety in Male Rats |
| title_short | Effect of Hydroalchoholic Extract 0f Trachyspermum Copticum on Anxiety in Male Rats |
| title_sort | effect of hydroalchoholic extract 0f trachyspermum copticum on anxiety in male rats |
| topic | hydroalcoholic extract trachyspermum copticum anxiety elevated plus maze male rats |
| url | https://sjoapb.qom.iau.ir/article_665016_b4721fb53fb41f86aa89799ea914b2f4.pdf |
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