Imaging characteristics, tissue distribution, and spread of a novel oncolytic vaccinia virus carrying the human sodium iodide symporter.
<h4>Introduction</h4>Oncolytic viruses show promise for treating cancer. However, to assess therapy and potential toxicity, a noninvasive imaging modality is needed. This study aims to determine the in vivo biodistribution, and imaging and timing characteristics of a vaccinia virus, GLV-...
मुख्य लेखकों: | Dana Haddad, Chun-Hao Chen, Sean Carlin, Gerd Silberhumer, Nanhai G Chen, Qian Zhang, Valerie Longo, Susanne G Carpenter, Arjun Mittra, Joshua Carson, Joyce Au, Mithat Gonen, Pat B Zanzonico, Aladar A Szalay, Yuman Fong |
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स्वरूप: | लेख |
भाषा: | English |
प्रकाशित: |
Public Library of Science (PLoS)
2012-01-01
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श्रृंखला: | PLoS ONE |
ऑनलाइन पहुंच: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22912675/?tool=EBI |
समान संसाधन
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Insertion of the human sodium iodide symporter to facilitate deep tissue imaging does not alter oncolytic or replication capability of a novel vaccinia virus
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Molecular network, pathway, and functional analysis of time-dependent gene changes associated with pancreatic cancer susceptibility to oncolytic vaccinia virotherapy
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Oncolytic vaccinia therapy of squamous cell carcinoma
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Oncolytic vaccinia virus GLV-1h68 strain shows enhanced replication in human breast cancer stem-like cells in comparison to breast cancer cells
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