Imaging characteristics, tissue distribution, and spread of a novel oncolytic vaccinia virus carrying the human sodium iodide symporter.

Imaging characteristics, tissue distribution, and spread of a novel oncolytic vaccinia virus carrying the human sodium iodide symporter.

<h4>Introduction</h4>Oncolytic viruses show promise for treating cancer. However, to assess therapy and potential toxicity, a noninvasive imaging modality is needed. This study aims to determine the in vivo biodistribution, and imaging and timing characteristics of a vaccinia virus, GLV-...

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Main Authors: Dana Haddad, Chun-Hao Chen, Sean Carlin, Gerd Silberhumer, Nanhai G Chen, Qian Zhang, Valerie Longo, Susanne G Carpenter, Arjun Mittra, Joshua Carson, Joyce Au, Mithat Gonen, Pat B Zanzonico, Aladar A Szalay, Yuman Fong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22912675/?tool=EBI

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