Imaging characteristics, tissue distribution, and spread of a novel oncolytic vaccinia virus carrying the human sodium iodide symporter.
<h4>Introduction</h4>Oncolytic viruses show promise for treating cancer. However, to assess therapy and potential toxicity, a noninvasive imaging modality is needed. This study aims to determine the in vivo biodistribution, and imaging and timing characteristics of a vaccinia virus, GLV-...
Main Authors: | Dana Haddad, Chun-Hao Chen, Sean Carlin, Gerd Silberhumer, Nanhai G Chen, Qian Zhang, Valerie Longo, Susanne G Carpenter, Arjun Mittra, Joshua Carson, Joyce Au, Mithat Gonen, Pat B Zanzonico, Aladar A Szalay, Yuman Fong |
---|---|
Format: | Article |
Jezik: | English |
Izdano: |
Public Library of Science (PLoS)
2012-01-01
|
Serija: | PLoS ONE |
Online dostop: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22912675/?tool=EBI |
Podobne knjige/članki
-
Insertion of the human sodium iodide symporter to facilitate deep tissue imaging does not alter oncolytic or replication capability of a novel vaccinia virus
od: Mittra Arjun, et al.
Izdano: (2011-03-01) -
Molecular network, pathway, and functional analysis of time-dependent gene changes associated with pancreatic cancer susceptibility to oncolytic vaccinia virotherapy
od: Dana Haddad, et al.
Izdano: (2016-01-01) -
Oncolytic vaccinia therapy of squamous cell carcinoma
od: Yu Yong A, et al.
Izdano: (2009-07-01) -
Replication efficiency of oncolytic vaccinia virus in cell cultures prognosticates the virulence and antitumor efficacy in mice
od: Yu Yong A, et al.
Izdano: (2011-09-01) -
Oncolytic vaccinia virus GLV-1h68 strain shows enhanced replication in human breast cancer stem-like cells in comparison to breast cancer cells
od: Wang Huiqiang, et al.
Izdano: (2012-08-01)