Predictive value of risk score using Kyoto classification of gastritis a few years prior to diagnosis of early gastric cancer
Abstract Background and Aim Based on past diagnostic classifications of gastritis, the Kyoto classification of gastritis adopts simpler, more objective gastritis findings according to Helicobacter pylori infection status and evaluates the risk of gastric cancer. To clarify whether this score can pre...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-02-01
|
| Series: | JGH Open |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/jgh3.12485 |
| _version_ | 1819135233728970752 |
|---|---|
| author | Yo Fujimoto Yasumi Katayama Yoshinori Gyotoku Ryosuke Oura Ikuhiro Kobori Tomoyuki Kitagawa Masaya Tamano |
| author_facet | Yo Fujimoto Yasumi Katayama Yoshinori Gyotoku Ryosuke Oura Ikuhiro Kobori Tomoyuki Kitagawa Masaya Tamano |
| author_sort | Yo Fujimoto |
| collection | DOAJ |
| description | Abstract Background and Aim Based on past diagnostic classifications of gastritis, the Kyoto classification of gastritis adopts simpler, more objective gastritis findings according to Helicobacter pylori infection status and evaluates the risk of gastric cancer. To clarify whether this score can predict future gastric cancer, we retrospectively examined risk scores obtained using the Kyoto classification of gastritis a few years prior to the diagnosis of early gastric cancer. Methods We reviewed data from 50 individuals who had undergone upper gastrointestinal endoscopy 2–3 years prior to the diagnosis of early gastric cancer in our hospital. Two expert endoscopists evaluated and compared risk scores obtained using the Kyoto classification of gastritis between cancer and control groups. Results With regard to the risk score obtained using the Kyoto classification of gastritis in all cases, atrophy, intestinal metaplasia, diffuse redness, and total score were significantly higher among gastric cancer cases. Among H. pylori‐eradicated cases, atrophy score was higher in the gastric cancer group. Among patients for whom H. pylori had been eradicated for >3 years at first endoscopy, atrophy score was still higher in the gastric cancer group. Conclusion This retrospective study suggested that the risk score obtained using the Kyoto classification of gastritis was useful for predicting the onset of gastric cancer. In particular, patients with a high atrophy score even after H. pylori eradication may be at high risk of developing gastric cancer. |
| first_indexed | 2024-12-22T10:15:50Z |
| format | Article |
| id | doaj.art-0e700047af6c47f88f06d51ae4a01a99 |
| institution | Directory Open Access Journal |
| issn | 2397-9070 |
| language | English |
| last_indexed | 2024-12-22T10:15:50Z |
| publishDate | 2021-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | JGH Open |
| spelling | doaj.art-0e700047af6c47f88f06d51ae4a01a992022-12-21T18:29:43ZengWileyJGH Open2397-90702021-02-015228028510.1002/jgh3.12485Predictive value of risk score using Kyoto classification of gastritis a few years prior to diagnosis of early gastric cancerYo Fujimoto0Yasumi Katayama1Yoshinori Gyotoku2Ryosuke Oura3Ikuhiro Kobori4Tomoyuki Kitagawa5Masaya Tamano6Department of Gastroenterology Dokkyo Medical University Saitama Medical Center Koshigaya City JapanDepartment of Gastroenterology Dokkyo Medical University Saitama Medical Center Koshigaya City JapanDepartment of Gastroenterology Dokkyo Medical University Saitama Medical Center Koshigaya City JapanDepartment of Gastroenterology Dokkyo Medical University Saitama Medical Center Koshigaya City JapanDepartment of Gastroenterology Dokkyo Medical University Saitama Medical Center Koshigaya City JapanDepartment of Gastroenterology Dokkyo Medical University Saitama Medical Center Koshigaya City JapanDepartment of Gastroenterology Dokkyo Medical University Saitama Medical Center Koshigaya City JapanAbstract Background and Aim Based on past diagnostic classifications of gastritis, the Kyoto classification of gastritis adopts simpler, more objective gastritis findings according to Helicobacter pylori infection status and evaluates the risk of gastric cancer. To clarify whether this score can predict future gastric cancer, we retrospectively examined risk scores obtained using the Kyoto classification of gastritis a few years prior to the diagnosis of early gastric cancer. Methods We reviewed data from 50 individuals who had undergone upper gastrointestinal endoscopy 2–3 years prior to the diagnosis of early gastric cancer in our hospital. Two expert endoscopists evaluated and compared risk scores obtained using the Kyoto classification of gastritis between cancer and control groups. Results With regard to the risk score obtained using the Kyoto classification of gastritis in all cases, atrophy, intestinal metaplasia, diffuse redness, and total score were significantly higher among gastric cancer cases. Among H. pylori‐eradicated cases, atrophy score was higher in the gastric cancer group. Among patients for whom H. pylori had been eradicated for >3 years at first endoscopy, atrophy score was still higher in the gastric cancer group. Conclusion This retrospective study suggested that the risk score obtained using the Kyoto classification of gastritis was useful for predicting the onset of gastric cancer. In particular, patients with a high atrophy score even after H. pylori eradication may be at high risk of developing gastric cancer.https://doi.org/10.1002/jgh3.12485endoscopygastric cancergastritisHelicobacter pyloriKyoto classification |
| spellingShingle | Yo Fujimoto Yasumi Katayama Yoshinori Gyotoku Ryosuke Oura Ikuhiro Kobori Tomoyuki Kitagawa Masaya Tamano Predictive value of risk score using Kyoto classification of gastritis a few years prior to diagnosis of early gastric cancer JGH Open endoscopy gastric cancer gastritis Helicobacter pylori Kyoto classification |
| title | Predictive value of risk score using Kyoto classification of gastritis a few years prior to diagnosis of early gastric cancer |
| title_full | Predictive value of risk score using Kyoto classification of gastritis a few years prior to diagnosis of early gastric cancer |
| title_fullStr | Predictive value of risk score using Kyoto classification of gastritis a few years prior to diagnosis of early gastric cancer |
| title_full_unstemmed | Predictive value of risk score using Kyoto classification of gastritis a few years prior to diagnosis of early gastric cancer |
| title_short | Predictive value of risk score using Kyoto classification of gastritis a few years prior to diagnosis of early gastric cancer |
| title_sort | predictive value of risk score using kyoto classification of gastritis a few years prior to diagnosis of early gastric cancer |
| topic | endoscopy gastric cancer gastritis Helicobacter pylori Kyoto classification |
| url | https://doi.org/10.1002/jgh3.12485 |
| work_keys_str_mv | AT yofujimoto predictivevalueofriskscoreusingkyotoclassificationofgastritisafewyearspriortodiagnosisofearlygastriccancer AT yasumikatayama predictivevalueofriskscoreusingkyotoclassificationofgastritisafewyearspriortodiagnosisofearlygastriccancer AT yoshinorigyotoku predictivevalueofriskscoreusingkyotoclassificationofgastritisafewyearspriortodiagnosisofearlygastriccancer AT ryosukeoura predictivevalueofriskscoreusingkyotoclassificationofgastritisafewyearspriortodiagnosisofearlygastriccancer AT ikuhirokobori predictivevalueofriskscoreusingkyotoclassificationofgastritisafewyearspriortodiagnosisofearlygastriccancer AT tomoyukikitagawa predictivevalueofriskscoreusingkyotoclassificationofgastritisafewyearspriortodiagnosisofearlygastriccancer AT masayatamano predictivevalueofriskscoreusingkyotoclassificationofgastritisafewyearspriortodiagnosisofearlygastriccancer |