Mechanistic and structural studies reveal NRAP-1-dependent coincident activation of NMDARs

Mechanistic and structural studies reveal NRAP-1-dependent coincident activation of NMDARs

Summary: N-methyl-D-aspartate (NMDA)-type ionotropic glutamate receptors have essential roles in neurotransmission and synaptic plasticity. Previously, we identified an evolutionarily conserved protein, NRAP-1, that is required for NMDA receptor (NMDAR) function in C. elegans. Here, we demonstrate t...

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Bibliographic Details
Main Authors: Dayton J. Goodell, Frank G. Whitby, Jerry E. Mellem, Ning Lei, Penelope J. Brockie, Aleksander J. Maricq, Debra M. Eckert, Christopher P. Hill, David M. Madsen, Andres V. Maricq
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Cell Reports
Subjects:
CP: Molecular biology
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724000226

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