Lower Urinary Tract Symptoms in Elderly Population With Multiple Sclerosis
Purpose The aim of this study is to compare the clinical and urodynamic characteristics of urinary disorders in multiple sclerosis (MS) patients in a geriatric population with a nongeriatric population. Methods This study was conducted retrospectively between 2010 and 2016. Each patient with MS aged...
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| Format: | Article |
| Language: | English |
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Korean Continence Society
2018-03-01
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| Series: | International Neurourology Journal |
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| Online Access: | http://www.einj.org/upload/pdf/inj-1835054-527.pdf |
| _version_ | 1818539983417376768 |
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| author | Camille Chesnel Audrey Charlanes Claire Hentzen Nicolas Turmel Frédérique Le Breton Samer Sheikh Ismael Gérard Amarenco |
| author_facet | Camille Chesnel Audrey Charlanes Claire Hentzen Nicolas Turmel Frédérique Le Breton Samer Sheikh Ismael Gérard Amarenco |
| author_sort | Camille Chesnel |
| collection | DOAJ |
| description | Purpose The aim of this study is to compare the clinical and urodynamic characteristics of urinary disorders in multiple sclerosis (MS) patients in a geriatric population with a nongeriatric population. Methods This study was conducted retrospectively between 2010 and 2016. Each patient with MS aged 65 and older was matched with 2 patients with MS aged less than 65 in sex, form of MS, and Expended Disability Status Scale (EDSS). Demographic data, urinary symptoms, treatment, quality of life, repercussion of lower urinary tract symptoms on daily life activities and psychological state and urodynamic parameters were collected. Differences between the 2 populations were evaluated using Student test, chi-square, or Fischer tests. Results Twenty-four patients with MS aged 65 and older (mean age, 69.8 years) were matched with 48 patients aged less than 65 years (mean age, 49.4 years). Maximum urethral closure pressure was lower in the elderly population than in the nongeriatric population (mean±standard deviation [SD]: 35.6±18.5 cm H<sub>2</sub>O vs. 78.2±52.3 cm H<sub>2</sub>O, P<0.001). In the male population, there was no statistical difference in any other clinical or urodynamic endpoints. In the female population, voiding symptoms was more described in the nongeriatric population (Urinary Symptom Profile low stream: 3.4±3.5 vs. 1.7±2.4, P=0.04), geriatric population had less urinary treatment (P=0.05). LUTS had less impact on quality of life (Qualiveen: 1.4±1.0 vs. 2.1±0.9, P=0.02) on the geriatric population than in the nongeriatric of female MS patients. Conclusions Geriatric population of MS has few differences of urinary disorders compared to a nongeriatric population with EDSS, sex, and MS form equal. However, the psychological impact of these urinary disorders is less important in female geriatric population. |
| first_indexed | 2024-12-11T21:49:21Z |
| format | Article |
| id | doaj.art-0e722ff5affc48b6ad6aa03e4278d6e4 |
| institution | Directory Open Access Journal |
| issn | 2093-4777 2093-6931 |
| language | English |
| last_indexed | 2024-12-11T21:49:21Z |
| publishDate | 2018-03-01 |
| publisher | Korean Continence Society |
| record_format | Article |
| series | International Neurourology Journal |
| spelling | doaj.art-0e722ff5affc48b6ad6aa03e4278d6e42022-12-22T00:49:31ZengKorean Continence SocietyInternational Neurourology Journal2093-47772093-69312018-03-01221586410.5213/inj.1835054.527714Lower Urinary Tract Symptoms in Elderly Population With Multiple SclerosisCamille Chesnel0Audrey Charlanes1Claire Hentzen2Nicolas Turmel3Frédérique Le Breton4Samer Sheikh Ismael5Gérard Amarenco6 GREEN GRC-01 UPMC (Group of clinical REsEarch in Neurouology), Sorbonne University, Paris, France GREEN GRC-01 UPMC (Group of clinical REsEarch in Neurouology), Sorbonne University, Paris, France GREEN GRC-01 UPMC (Group of clinical REsEarch in Neurouology), Sorbonne University, Paris, France GREEN GRC-01 UPMC (Group of clinical REsEarch in Neurouology), Sorbonne University, Paris, France GREEN GRC-01 UPMC (Group of clinical REsEarch in Neurouology), Sorbonne University, Paris, France GREEN GRC-01 UPMC (Group of clinical REsEarch in Neurouology), Sorbonne University, Paris, France GREEN GRC-01 UPMC (Group of clinical REsEarch in Neurouology), Sorbonne University, Paris, FrancePurpose The aim of this study is to compare the clinical and urodynamic characteristics of urinary disorders in multiple sclerosis (MS) patients in a geriatric population with a nongeriatric population. Methods This study was conducted retrospectively between 2010 and 2016. Each patient with MS aged 65 and older was matched with 2 patients with MS aged less than 65 in sex, form of MS, and Expended Disability Status Scale (EDSS). Demographic data, urinary symptoms, treatment, quality of life, repercussion of lower urinary tract symptoms on daily life activities and psychological state and urodynamic parameters were collected. Differences between the 2 populations were evaluated using Student test, chi-square, or Fischer tests. Results Twenty-four patients with MS aged 65 and older (mean age, 69.8 years) were matched with 48 patients aged less than 65 years (mean age, 49.4 years). Maximum urethral closure pressure was lower in the elderly population than in the nongeriatric population (mean±standard deviation [SD]: 35.6±18.5 cm H<sub>2</sub>O vs. 78.2±52.3 cm H<sub>2</sub>O, P<0.001). In the male population, there was no statistical difference in any other clinical or urodynamic endpoints. In the female population, voiding symptoms was more described in the nongeriatric population (Urinary Symptom Profile low stream: 3.4±3.5 vs. 1.7±2.4, P=0.04), geriatric population had less urinary treatment (P=0.05). LUTS had less impact on quality of life (Qualiveen: 1.4±1.0 vs. 2.1±0.9, P=0.02) on the geriatric population than in the nongeriatric of female MS patients. Conclusions Geriatric population of MS has few differences of urinary disorders compared to a nongeriatric population with EDSS, sex, and MS form equal. However, the psychological impact of these urinary disorders is less important in female geriatric population.http://www.einj.org/upload/pdf/inj-1835054-527.pdfElderlyLower urinary tract symptomsMultiple sclerosis |
| spellingShingle | Camille Chesnel Audrey Charlanes Claire Hentzen Nicolas Turmel Frédérique Le Breton Samer Sheikh Ismael Gérard Amarenco Lower Urinary Tract Symptoms in Elderly Population With Multiple Sclerosis International Neurourology Journal Elderly Lower urinary tract symptoms Multiple sclerosis |
| title | Lower Urinary Tract Symptoms in Elderly Population With Multiple Sclerosis |
| title_full | Lower Urinary Tract Symptoms in Elderly Population With Multiple Sclerosis |
| title_fullStr | Lower Urinary Tract Symptoms in Elderly Population With Multiple Sclerosis |
| title_full_unstemmed | Lower Urinary Tract Symptoms in Elderly Population With Multiple Sclerosis |
| title_short | Lower Urinary Tract Symptoms in Elderly Population With Multiple Sclerosis |
| title_sort | lower urinary tract symptoms in elderly population with multiple sclerosis |
| topic | Elderly Lower urinary tract symptoms Multiple sclerosis |
| url | http://www.einj.org/upload/pdf/inj-1835054-527.pdf |
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