Discovery of Sulforaphane as an Inducer of Ferroptosis in U-937 Leukemia Cells: Expanding Its Anticancer Potential

Discovery of Sulforaphane as an Inducer of Ferroptosis in U-937 Leukemia Cells: Expanding Its Anticancer Potential

In recent years, natural compounds have emerged as inducers of non-canonical cell death. The isothiocyanate sulforaphane (SFN) is a well-known natural anticancer compound with remarkable pro-apoptotic activity. Its ability to promote non-apoptotic cell-death mechanisms remains poorly investigated. T...

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Bibliographic Details
Main Authors: Giulia Greco, Michael Schnekenburger, Elena Catanzaro, Eleonora Turrini, Fabio Ferrini, Piero Sestili, Marc Diederich, Carmela Fimognari
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
natural products
sulforaphane
anticancer activity
non-canonical cell death
ferroptosis
necroptosis
Online Access:https://www.mdpi.com/2072-6694/14/1/76

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