High-level expression of leghemoglobin in Kluyveromyces marxianus by remodeling the heme metabolism pathway

High-level expression of leghemoglobin in Kluyveromyces marxianus by remodeling the heme metabolism pathway

Soy leghemoglobin, when bound to heme, imparts a meat-like color and flavor and can serve as a substitute for animal-derived proteins. Enhancing cellular heme synthesis improves the recombinant expression of leghemoglobin in yeast. To achieve high-level expression of leghemoglobin A (LBA) in Kluyver...

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Bibliographic Details
Main Authors: Tian Tian, Xinwei Wu, Pingping Wu, Xinyi Lu, Qi Wang, Yifan Lin, Canjie Liu, Jungang Zhou, Yao Yu, Hong Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Kluyveromyces marxianus
leghemoglobin
heme biosynthesis
yeast artificial chromosomes
high-level expression
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1329016/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1329016/full

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